| Literature DB >> 17057751 |
John G Albeck1, Gavin MacBeath, Forest M White, Peter K Sorger, Douglas A Lauffenburger, Suzanne Gaudet.
Abstract
Systems biology, particularly of mammalian cells, is data starved. However, technologies are now in place to obtain rich data, in a form suitable for model construction and validation, that describes the activities, states and locations of cell-signalling molecules. The key is to use several measurement technologies simultaneously and, recognizing each of their limits, to assemble a self-consistent compendium of systematic data.Entities:
Mesh:
Year: 2006 PMID: 17057751 DOI: 10.1038/nrm2042
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN: 1471-0072 Impact factor: 94.444