Literature DB >> 17057751

Collecting and organizing systematic sets of protein data.

John G Albeck1, Gavin MacBeath, Forest M White, Peter K Sorger, Douglas A Lauffenburger, Suzanne Gaudet.   

Abstract

Systems biology, particularly of mammalian cells, is data starved. However, technologies are now in place to obtain rich data, in a form suitable for model construction and validation, that describes the activities, states and locations of cell-signalling molecules. The key is to use several measurement technologies simultaneously and, recognizing each of their limits, to assemble a self-consistent compendium of systematic data.

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Year:  2006        PMID: 17057751     DOI: 10.1038/nrm2042

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  43 in total

1.  An integrated stochastic model of "inside-out" integrin activation and selective T-lymphocyte recruitment.

Authors:  Michael T Beste; Dooyoung Lee; Michael R King; Gary A Koretzky; Daniel A Hammer
Journal:  Langmuir       Date:  2012-01-04       Impact factor: 3.882

Review 2.  Systems biology in immunology: a computational modeling perspective.

Authors:  Ronald N Germain; Martin Meier-Schellersheim; Aleksandra Nita-Lazar; Iain D C Fraser
Journal:  Annu Rev Immunol       Date:  2011       Impact factor: 28.527

3.  Dendritic cell responses to surface properties of clinical titanium surfaces.

Authors:  Peng Meng Kou; Zvi Schwartz; Barbara D Boyan; Julia E Babensee
Journal:  Acta Biomater       Date:  2010-10-25       Impact factor: 8.947

Review 4.  Molecular simulations of protein dynamics: new windows on mechanisms in biology.

Authors:  Guy G Dodson; David P Lane; Chandra S Verma
Journal:  EMBO Rep       Date:  2008-02       Impact factor: 8.807

Review 5.  Models of signalling networks - what cell biologists can gain from them and give to them.

Authors:  Kevin A Janes; Douglas A Lauffenburger
Journal:  J Cell Sci       Date:  2013-05-01       Impact factor: 5.285

6.  A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations.

Authors:  Yingting Liu; Jeremy Purvis; Andrew Shih; Joshua Weinstein; Neeraj Agrawal; Ravi Radhakrishnan
Journal:  Ann Biomed Eng       Date:  2007-02-02       Impact factor: 3.934

7.  Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society.

Authors:  Rehan Akbani; Karl-Friedrich Becker; Neil Carragher; Ted Goldstein; Leanne de Koning; Ulrike Korf; Lance Liotta; Gordon B Mills; Satoshi S Nishizuka; Michael Pawlak; Emanuel F Petricoin; Harvey B Pollard; Bryan Serrels; Jingchun Zhu
Journal:  Mol Cell Proteomics       Date:  2014-04-28       Impact factor: 5.911

8.  Cytokine-induced signaling networks prioritize dynamic range over signal strength.

Authors:  Kevin A Janes; H Christian Reinhardt; Michael B Yaffe
Journal:  Cell       Date:  2008-10-17       Impact factor: 41.582

Review 9.  Navigating the network: signaling cross-talk in hematopoietic cells.

Authors:  Iain D C Fraser; Ronald N Germain
Journal:  Nat Immunol       Date:  2009-03-19       Impact factor: 25.606

10.  Reverse Phase Protein Arrays for Compound Profiling.

Authors:  Nathan Moerke; Mohammad Fallahi-Sichani
Journal:  Curr Protoc Chem Biol       Date:  2016-09-13
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