OBJECTIVE: To comprehensively review and evaluate the direct costs of endometriosis. DESIGN AND SETTING: We systematically reviewed studies published since 1990, and conducted an analysis of publicly available national databases (Healthcare Cost and Utilization Project and National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey) in the United States. We assessed: [1] the overall economic impact of endometriosis; [2] the direct costs associated with specific treatments; and [3] the indirect costs of endometriosis associated with reduced work productivity. RESULTS: Of 13 published studies meeting inclusion criteria, 11 (85%) addressed direct costs, a few studies addressed outpatient costs or indirect costs, and no study quantified the economic impact among adolescents. Direct endometriosis-related costs were considerable and appeared driven by hospitalizations. Our database analysis found: [1] as endometriosis-related hospital length of stay steadily declined from 1993 to 2002, per-patient cost increased 61%; [2] adolescents (aged 10-17 years) had endometriosis-related hospitalizations; [3] approximately 50% of >600,000 endometriosis-related ambulatory patient visits involved specialist care; and [4] females 23 years old or younger constituted >20% of endometriosis-related outpatient visits. CONCLUSIONS: Health economic information for endometriosis is scarce, limiting our understanding of its overall economic impact. Nevertheless, the literature and other available data suggest that endometriosis places a considerable burden on patients and society.
OBJECTIVE: To comprehensively review and evaluate the direct costs of endometriosis. DESIGN AND SETTING: We systematically reviewed studies published since 1990, and conducted an analysis of publicly available national databases (Healthcare Cost and Utilization Project and National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey) in the United States. We assessed: [1] the overall economic impact of endometriosis; [2] the direct costs associated with specific treatments; and [3] the indirect costs of endometriosis associated with reduced work productivity. RESULTS: Of 13 published studies meeting inclusion criteria, 11 (85%) addressed direct costs, a few studies addressed outpatient costs or indirect costs, and no study quantified the economic impact among adolescents. Direct endometriosis-related costs were considerable and appeared driven by hospitalizations. Our database analysis found: [1] as endometriosis-related hospital length of stay steadily declined from 1993 to 2002, per-patient cost increased 61%; [2] adolescents (aged 10-17 years) had endometriosis-related hospitalizations; [3] approximately 50% of >600,000 endometriosis-related ambulatory patient visits involved specialist care; and [4] females 23 years old or younger constituted >20% of endometriosis-related outpatient visits. CONCLUSIONS: Health economic information for endometriosis is scarce, limiting our understanding of its overall economic impact. Nevertheless, the literature and other available data suggest that endometriosis places a considerable burden on patients and society.
Authors: Grant W Montgomery; Dale R Nyholt; Zhen Zhen Zhao; Susan A Treloar; Jodie N Painter; Stacey A Missmer; Stephen H Kennedy; Krina T Zondervan Journal: Hum Reprod Update Date: 2008-06-05 Impact factor: 15.610
Authors: Carla Regina Schmitz; Carlos Augusto Bastos de Souza; Vanessa Krebs Genro; Ursula Matte; Emily de Conto; João Sabino Cunha-Filho Journal: J Assist Reprod Genet Date: 2015-05-03 Impact factor: 3.412
Authors: Hakan Mete Karalok; Ebru Aydin; Ozlen Saglam; Aysenur Torun; Ozlem Guzeloglu-Kayisli; Maria D Lalioti; Helena Kristiansson; Cindy M P Duke; Gina Choe; Clare Flannery; Caleb B Kallen; Emre Seli Journal: J Clin Endocrinol Metab Date: 2014-12 Impact factor: 5.958
Authors: E Maria C Ohlsson Teague; Kylie H Van der Hoek; Mark B Van der Hoek; Naomi Perry; Prabhath Wagaarachchi; Sarah A Robertson; Cristin G Print; Louise M Hull Journal: Mol Endocrinol Date: 2008-12-12