Literature DB >> 27681777

[Endometriosis : An often unrecognized pain disorder].

S Mechsner1.   

Abstract

Endometriosis is a chronic disease of women during their reproductive age. The most typical symptoms are dysmenorrhoea, dyspareunia, dysuria, cyclical and acyclical pelvic pain, bleeding disorders and infertility. These symptoms lead to significant impairment of the quality of life and economic burden. The prevalence is estimated to be 2-20 % of all women in this age and due to this fact, it is one of the most frequently benign gynecological diseases. Not all women suffer from severe symptoms, but more than 50 % require ongoing treatment. Beside the severe physical impairment due to the pain, the high recurrence rate of 50-80 % also after surgical and/or hormonal treatment is problematic. The interval between onset of symptoms and diagnosis is approximately 6-8 years. These problems are a consequence of lack of knowledge about the pathogenesis of the disease and the pain mechanisms as well as the lack of awareness of physicians in this field.

Entities:  

Keywords:  Dysmenorrhea; Dyspareunia; Dysuria; Infertility; Pelvic pain

Mesh:

Year:  2016        PMID: 27681777     DOI: 10.1007/s00482-016-0154-1

Source DB:  PubMed          Journal:  Schmerz        ISSN: 0932-433X            Impact factor:   1.107


  24 in total

1.  Deep infiltrating endometriosis: relation between severity of dysmenorrhoea and extent of disease.

Authors:  Charles Chapron; Arnaud Fauconnier; Jean-Bernard Dubuisson; Habib Barakat; Marco Vieira; Gérard Bréart
Journal:  Hum Reprod       Date:  2003-04       Impact factor: 6.918

2.  Distinct mechanisms regulate cyclooxygenase-1 and -2 in peritoneal macrophages of women with and without endometriosis.

Authors:  Meng-Hsing Wu; H Sunny Sun; Chen-Chung Lin; Kuei-Yang Hsiao; Pei-Chin Chuang; Hsien-An Pan; Shaw-Jenq Tsai
Journal:  Mol Hum Reprod       Date:  2002-12       Impact factor: 4.025

3.  Laparoscopic uterine biopsy for diagnosing diffuse adenomyosis.

Authors:  P Vercellini; L Trespidi; S Panazza; T Bramante; F Mauro; P G Crosignani
Journal:  J Reprod Med       Date:  1996-04       Impact factor: 0.142

4.  Interleukin 1beta, interleukin-6, and tumor necrosis factor-alpha in endometriotic tissue and in endometrium.

Authors:  A Bergqvist; C Bruse; M Carlberg; K Carlström
Journal:  Fertil Steril       Date:  2001-03       Impact factor: 7.329

5.  Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosis.

Authors:  H Ota; S Igarashi; M Sasaki; T Tanaka
Journal:  Hum Reprod       Date:  2001-03       Impact factor: 6.918

6.  Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain.

Authors:  P R Koninckx; C Meuleman; S Demeyere; E Lesaffre; F J Cornillie
Journal:  Fertil Steril       Date:  1991-04       Impact factor: 7.329

7.  Classification of endometriotic implants by morphologic appearance and capacity to synthesize prostaglandin F.

Authors:  M W Vernon; J S Beard; K Graves; E A Wilson
Journal:  Fertil Steril       Date:  1986-11       Impact factor: 7.329

8.  Macrophages and nerve fibres in peritoneal endometriosis.

Authors:  Lu Vinh Phuc Tran; Natsuko Tokushige; Marina Berbic; Robert Markham; Ian S Fraser
Journal:  Hum Reprod       Date:  2009-01-09       Impact factor: 6.918

Review 9.  Chronic pelvic pain in women: etiology, pathogenesis and diagnostic approach.

Authors:  Paolo Vercellini; Edgardo Somigliana; Paola Viganò; Annalisa Abbiati; Giussy Barbara; Luigi Fedele
Journal:  Gynecol Endocrinol       Date:  2009-03       Impact factor: 2.260

10.  Peritoneal fluid thromboxane B2 and 6-keto-prostaglandin F1 alpha in endometriosis.

Authors:  T S Drake; W F O'Brien; P W Ramwell; S A Metz
Journal:  Am J Obstet Gynecol       Date:  1981-06-15       Impact factor: 8.661

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  4 in total

1.  Chronic Pelvic Pain in Endometriosis: Cross-Sectional Associations with Mental Disorders, Sexual Dysfunctions and Childhood Maltreatment.

Authors:  Johanna Netzl; Burkhard Gusy; Barbara Voigt; Jalid Sehouli; Sylvia Mechsner
Journal:  J Clin Med       Date:  2022-06-27       Impact factor: 4.964

2.  Hyaluronic Acid-Modified Nanoplatforms as a Vector for Targeted Delivery of Autophagy-Related Gene to the Endometriotic Lesions in Mice.

Authors:  Mengdan Zhao; Meng Zhang; Qin Yu; Weidong Fei; Tiantian Li; Libo Zhu; Yao Yao; Caihong Zheng; Xinmei Zhang
Journal:  Front Bioeng Biotechnol       Date:  2022-07-01

Review 3.  [Management of endometriosis pain : Stage-based treatment strategies and clinical experience].

Authors:  Sylvia Mechsner
Journal:  Schmerz       Date:  2021-03-11       Impact factor: 1.107

Review 4.  Endometriosis, an Ongoing Pain-Step-by-Step Treatment.

Authors:  Sylvia Mechsner
Journal:  J Clin Med       Date:  2022-01-17       Impact factor: 4.241

  4 in total

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