Literature DB >> 17055332

Bioorthogonal noncovalent chemistry: Fluorous phases in chemical biology.

Nicholas C Yoder1, Deniz Yüksel, Laila Dafik, Krishna Kumar.   

Abstract

Chemical entities designed to noncovalently interact with predetermined partners have fashioned a new paradigm in chemical biology. Fluorocarbons are extremely promising as supramolecular synthons toward these objectives. Bioorthogonal noncovalent interactions provide a way to modulate self-assembled systems in environments where such control has hitherto not been possible. Fluorocarbons have now found applications in self-assembly as well as proteomics, biomolecule purification and in the creation of microarray platforms. Other self-assembly motifs with similar attributes might be exploited using the same general approach.

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Year:  2006        PMID: 17055332     DOI: 10.1016/j.cbpa.2006.10.007

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  15 in total

1.  Structural basis for the enhanced stability of highly fluorinated proteins.

Authors:  Benjamin C Buer; Jennifer L Meagher; Jeanne A Stuckey; E Neil G Marsh
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-12       Impact factor: 11.205

Review 2.  Fluorine: a new element in protein design.

Authors:  Benjamin C Buer; E Neil G Marsh
Journal:  Protein Sci       Date:  2012-02-14       Impact factor: 6.725

3.  Modulation of cellular adhesion by glycoengineering.

Authors:  Laila Dafik; Marc d'Alarcao; Krishna Kumar
Journal:  J Med Chem       Date:  2010-05-27       Impact factor: 7.446

4.  Base-catalyzed diastereoselective trimerization of trifluoroacetone.

Authors:  Anthony P Silvestri; Philip E Dawson
Journal:  Org Biomol Chem       Date:  2017-06-08       Impact factor: 3.876

5.  Comparison of the structures and stabilities of coiled-coil proteins containing hexafluoroleucine and t-butylalanine provides insight into the stabilizing effects of highly fluorinated amino acid side-chains.

Authors:  Benjamin C Buer; Jennifer L Meagher; Jeanne A Stuckey; E Neil G Marsh
Journal:  Protein Sci       Date:  2012-10-01       Impact factor: 6.725

6.  Sialidases as regulators of bioengineered cellular surfaces.

Authors:  Cristina Y Zamora; Matthew J Ryan; Marc d'Alarcao; Krishna Kumar
Journal:  Glycobiology       Date:  2015-03-20       Impact factor: 4.313

7.  Hydration dynamics at fluorinated protein surfaces.

Authors:  Oh-Hoon Kwon; Tae Hyeon Yoo; Christina M Othon; James A Van Deventer; David A Tirrell; Ahmed H Zewail
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-20       Impact factor: 11.205

8.  Fluorination of mammalian cell surfaces via the sialic acid biosynthetic pathway.

Authors:  Laila Dafik; Marc d'Alarcao; Krishna Kumar
Journal:  Bioorg Med Chem Lett       Date:  2008-09-06       Impact factor: 2.823

9.  Cross-strand interactions of fluorinated amino acids in β-hairpin constructs.

Authors:  Ginevra A Clark; James D Baleja; Krishna Kumar
Journal:  J Am Chem Soc       Date:  2012-10-18       Impact factor: 15.419

10.  Highly efficient and selective enrichment of peptide subsets combining fluorous chemistry with reversed-phase chromatography.

Authors:  Wantao Ying; David H Perlman; Lei Li; Roger Théberge; Catherine E Costello; Mark E McComb
Journal:  Rapid Commun Mass Spectrom       Date:  2009-12       Impact factor: 2.419

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