| Literature DB >> 17053317 |
Tadaatsu Imaizumi1, Hiroshi Sashinami, Fumiaki Mori, Tomoh Matsumiya, Hidemi Yoshida, Akio Nakane, Koichi Wakabayashi, Chikara Oyama, Kei Satoh.
Abstract
Retinoic acid-inducible gene-I (RIG-I) is considered to play a role in innate immunity against virus infections. We showed by immunohistochemical study that RIG-I expression is upregulated in vivo in hepatic Kupffer cells and in splenic reticular cells of mice infected with Listeria monocytogenes. Both heat-killed L. monocytogenes and live L. monocytogenes induced the expression of RIG-I in cultured RAW264.7 murine macrophage-like cells in vitro. RIG-I may also be involved in innate immunity against Listeria infection.Entities:
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Year: 2006 PMID： 17053317 DOI： 10.1111/j.1348-0421.2006.tb03857.x
Source DB: PubMed Journal: Microbiol Immunol ISSN： 0385-5600 Impact factor: 1.955