Literature DB >> 17046432

Sodium intake and hypertension.

Heikki Karppanen1, Eero Mervaala.   

Abstract

In current diets, the level of sodium is very high, whereas that of potassium, calcium, and magnesium is low compared with the level in diets composed of unprocessed, natural foods. We present the biologic rationale and scientific evidence that show that the current salt intake levels largely explain the high prevalence of hypertension. Comprehensive reduction of salt intake, both alone and particularly in combination with increases in intakes of potassium, calcium, and magnesium, is able to lower average blood pressure levels substantially. During the past 30 years, the one-third decrease in the average salt intake has been accompanied by a more than 10-mm Hg fall in the population average of both systolic and diastolic blood pressure, and a 75% to 80% decrease in both stroke and coronary heart disease mortality in Finland. There is no evidence of any harmful effects of salt reduction. Salt-reduction recommendations alone have a very small, if any, population impact. In the United States, for example, the per capita use of salt increased by approximately 55% from the mid-1980s to the late 1990s. We deal with factors that contribute toward increasing salt intakes and present examples of the methods that have contributed to the successful salt reduction in Finland.

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Year:  2006        PMID: 17046432     DOI: 10.1016/j.pcad.2006.07.001

Source DB:  PubMed          Journal:  Prog Cardiovasc Dis        ISSN: 0033-0620            Impact factor:   8.194


  109 in total

1.  Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health.

Authors:  Feng J He; Norm R C Campbell; Yuan Ma; Graham A MacGregor; Mary E Cogswell; Nancy R Cook
Journal:  Int J Epidemiol       Date:  2018-12-01       Impact factor: 7.196

Review 2.  Salt restriction for the prevention of cardiovascular disease.

Authors:  Dieter Klaus; Joachim Hoyer; Martin Middeke
Journal:  Dtsch Arztebl Int       Date:  2010-07-02       Impact factor: 5.594

Review 3.  Strategies for Achieving Healthy Vascular Aging.

Authors:  Kristen L Nowak; Matthew J Rossman; Michel Chonchol; Douglas R Seals
Journal:  Hypertension       Date:  2018-01-08       Impact factor: 10.190

4.  Salt and cardiovascular disease.

Authors:  Francesco P Cappuccio
Journal:  BMJ       Date:  2007-04-28

Review 5.  Hypertension: history and development of established and novel treatments.

Authors:  Milan Wolf; Sebastian Ewen; Felix Mahfoud; Michael Böhm
Journal:  Clin Res Cardiol       Date:  2018-06-27       Impact factor: 5.460

Review 6.  Effective population-wide public health interventions to promote sodium reduction.

Authors:  Sailesh Mohan; Norm R C Campbell; Kevin Willis
Journal:  CMAJ       Date:  2009-09-14       Impact factor: 8.262

7.  Time-course and mechanisms of restored vascular relaxation by reduced salt intake and angiotensin II infusion in rats fed a high-salt diet.

Authors:  Scott T McEwen; James R Schmidt; Lewis Somberg; Lourdes de la Cruz; Julian H Lombard
Journal:  Microcirculation       Date:  2009-02-23       Impact factor: 2.628

8.  N-geranyl cyclopropyl-carboximide modulates salty and umami taste in humans and animal models.

Authors:  Mark L Dewis; Tam-Hao T Phan; ZuoJun Ren; Xuanyu Meng; Meng Cui; Shobha Mummalaneni; Mee-Ra Rhyu; John A DeSimone; Vijay Lyall
Journal:  J Neurophysiol       Date:  2012-12-05       Impact factor: 2.714

9.  Restoration of cerebral vascular relaxation in renin congenic rats by introgression of the Dahl R renin gene.

Authors:  Ines Drenjancevic-Peric; Brian D Weinberg; Andrew S Greene; Julian H Lombard
Journal:  Am J Hypertens       Date:  2009-12-03       Impact factor: 2.689

10.  The salted artery and angiotensin II signaling: a deadly duo in arterial disease.

Authors:  Mingyi Wang; Edward G Lakatta
Journal:  J Hypertens       Date:  2009-01       Impact factor: 4.844

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