| Literature DB >> 17045703 |
Preeti Sharma1, Sangeeta Singh, Tanveer I Siddiqui, Vishnu S Singh, Bijoy Kundu, Philip Prathipati, Anil K Saxena, Dinesh K Dikshit, Leena Rastogi, Chetna Dixit, M B Gupta, G K Patnaik, Madhu Dikshit.
Abstract
In a program to identify new anti-ulcer compounds, a series of N-acyl derivatives of alpha-amino acids were screened for their in vitro H(+)/K(+) ATPase inhibitory activity, and in vivo efficacy in Pylorus ligation model. 3D-QSAR studies were carried out and a representative compound 13 was studied for the nature of its proton pump inhibition.Entities:
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Year: 2006 PMID： 17045703 DOI： 10.1016/j.ejmech.2006.08.016
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514