Literature DB >> 17041777

[Hyperplastic scars and keloids. Part I: basics and prevention].

A Baisch1, F Riedel.   

Abstract

Aberrant wound healing results in unsightly scarring, hypertrophic scarring, and keloid formation, causing functional and cosmetic deformities, discomfort, psychological stress, and patient dissatisfaction. Scar prevention and management continue to be important issues for the facial plastic surgeon. This article presents an overview on the pathogenesis of a scar and of the different types of scars. Differences between keloids, hypertrophic scars and normal scars include distinct scar appearance, histologic morphology and cellular function in response to growth factors. Recent advances in our understanding of the wound healing process reveal possible causes for hypertrophic scars and keloids. This information might assist in the development of efficacious prevention and treatment for hypertrophic scar and keloid formation. This article also describes the strategies available for scar prevention. Recommendations focus on the management of hypertrophic scars and keloids.

Entities:  

Mesh:

Year:  2006        PMID: 17041777     DOI: 10.1007/s00106-006-1462-z

Source DB:  PubMed          Journal:  HNO        ISSN: 0017-6192            Impact factor:   1.284


  137 in total

1.  Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy.

Authors:  N A Chowdri; M Masarat; A Mattoo; M A Darzi
Journal:  Aust N Z J Surg       Date:  1999-09

Review 2.  Cutaneous wound healing.

Authors:  A J Singer; R A Clark
Journal:  N Engl J Med       Date:  1999-09-02       Impact factor: 91.245

3.  Rating the resolving hypertrophic scar: comparison of the Vancouver Scar Scale and scar volume.

Authors:  B Nedelec; H A Shankowsky; E E Tredget
Journal:  J Burn Care Rehabil       Date:  2000 May-Jun

Review 4.  Wound dressings for office-based surgery.

Authors:  Gregg M Menaker
Journal:  Facial Plast Surg       Date:  2004-02       Impact factor: 1.446

5.  Effects of a water-impermeable, non-silicone-based occlusive dressing on keloids.

Authors:  H C Bieley; B Berman
Journal:  J Am Acad Dermatol       Date:  1996-07       Impact factor: 11.527

6.  A short course postoperative radiotherapy regime for keloid scars in Nigeria.

Authors:  F A Durosinmi-Etti; T A Olasinde; E O Solarin
Journal:  West Afr J Med       Date:  1994 Jan-Mar

7.  Histologic basis of keloid and hypertrophic scar differentiation. Clinicopathologic correlation.

Authors:  W R Blackburn; B Cosman
Journal:  Arch Pathol       Date:  1966-07

8.  Treatment of earlobe keloids with surgery plus adjuvant intralesional verapamil and pressure earrings.

Authors:  W T Lawrence
Journal:  Ann Plast Surg       Date:  1996-08       Impact factor: 1.539

Review 9.  Topical alpha-tocopherol acetate in the bulk phase: eight years of experience in skin treatment.

Authors:  Giorgio Panin; Renata Strumia; Fulvio Ursini
Journal:  Ann N Y Acad Sci       Date:  2004-12       Impact factor: 5.691

10.  Accelerated wound healing by in vivo application of keratinocytes overexpressing KGF.

Authors:  Jürgen Kopp; Guang Y Wang; Peter Kulmburg; Stefan Schultze-Mosgau; Jing N Huan; Kang Ying; Harun Seyhan; Mark D Jeschke; Ulrich Kneser; Alexander D Bach; Sheng D Ge; Steven Dooley; Raymund E Horch
Journal:  Mol Ther       Date:  2004-07       Impact factor: 11.454

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  8 in total

Review 1.  Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring.

Authors:  Meilang Xue; Christopher J Jackson
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-03-01       Impact factor: 4.730

2.  Role of verapamil in preventing and treating hypertrophic scars and keloids.

Authors:  Ru Wang; Yu Mao; Zhenyu Zhang; Zhengyong Li; Junjie Chen; Ying Cen
Journal:  Int Wound J       Date:  2015-05-12       Impact factor: 3.315

3.  [Recommendations for the prevention and therapy of hypertrophic scars and keloids].

Authors:  G G Gauglitz; C Kunte
Journal:  Hautarzt       Date:  2011-05       Impact factor: 0.751

Review 4.  Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis.

Authors:  YiMing Ren; XianHu Zhou; ZhiJian Wei; Wei Lin; BaoYou Fan; ShiQing Feng
Journal:  Int Wound J       Date:  2016-07-18       Impact factor: 3.315

Review 5.  Current Advances in Hypertrophic Scar and Keloid Management.

Authors:  Natasha Barone; Tyler Safran; Joshua Vorstenbosch; Peter G Davison; Sabrina Cugno; Amanda M Murphy
Journal:  Semin Plast Surg       Date:  2021-07-15       Impact factor: 2.195

6.  Topical 5 fluorouracil cream vs combined 5 fluorouracil and fractional erbium YAG laser for treatment of severe hypertrophic scars.

Authors:  Abeer Attia Tawfik; Maha Fathy; Ashraf Badawi; Noha Abdallah; Hisham Shokeir
Journal:  Clin Cosmet Investig Dermatol       Date:  2019-03-14

7.  A new CO2 laser technique for the treatment of pediatric hypertrophic burn scars: An observational study.

Authors:  Tomasz Żądkowski; Paweł Nachulewicz; Maciej Mazgaj; Magdalena Woźniak; Czesław Cielecki; Andrzej Paweł Wieczorek; Iwona Beń-Skowronek
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

Review 8.  Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis.

Authors:  Rei Ogawa
Journal:  Int J Mol Sci       Date:  2017-03-10       Impact factor: 5.923

  8 in total

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