Literature DB >> 10515339

Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy.

N A Chowdri1, M Masarat, A Mattoo, M A Darzi.   

Abstract

BACKGROUND: The management of keloids and hypertrophic scars continues to be controversial. Experience of treating 58 such lesions, 58.62% of which were recurrent, is presented.
METHODS: Each lesion was subjected to surgical excision with intra-operative local injection of triamcinolone acetonide, followed by repeat injection of the same drug at weekly intervals for 2-5 weeks depending on the symptomatic relief, and then monthly injections for 4-6 months.
RESULTS: Complete symptomatic relief was achieved in all patients within 5 weeks of surgery. Objective response in terms of no recurrence was noted in 91.9% of patients with keloids, and 95.24% of patients with hypertrophic scars at a mean follow-up of 30.5 months. Local or systemic complications were insignificant.
CONCLUSION: Because of promising results, further use and evaluation of this method of treatment is recommended for large, recurrent and complicated keloids and hypertrophic scars.

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Year:  1999        PMID: 10515339     DOI: 10.1046/j.1440-1622.1999.01658.x

Source DB:  PubMed          Journal:  Aust N Z J Surg        ISSN: 0004-8682


  15 in total

Review 1.  Therapy of auricular keloids: review of different treatment modalities and proposal for a therapeutic algorithm.

Authors:  K Froelich; R Staudenmaier; N Kleinsasser; R Hagen
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-07-13       Impact factor: 2.503

2.  [Hyperplastic scars and keloids. Part I: basics and prevention].

Authors:  A Baisch; F Riedel
Journal:  HNO       Date:  2006-11       Impact factor: 1.284

3.  Auricular keloids: treatment and results.

Authors:  Christian Bermueller; Gerhard Rettinger; Tilman Keck
Journal:  Eur Arch Otorhinolaryngol       Date:  2009-08-09       Impact factor: 2.503

4.  Treatment of refractory keloids with pulsed dye laser alone and with rotational pulsed dye laser and intralesional corticosteroids: A retrospective case series.

Authors:  S Stephanides; S Rai; Pj August; Je Ferguson; V Madan
Journal:  Laser Ther       Date:  2011

5.  [Recommendations for the prevention and therapy of hypertrophic scars and keloids].

Authors:  G G Gauglitz; C Kunte
Journal:  Hautarzt       Date:  2011-05       Impact factor: 0.751

Review 6.  Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions.

Authors:  Clement D Marshall; Michael S Hu; Tripp Leavitt; Leandra A Barnes; H Peter Lorenz; Michael T Longaker
Journal:  Adv Wound Care (New Rochelle)       Date:  2018-02-01       Impact factor: 4.730

7.  Serial In-Office Intralesional Steroid Injections in Airway Stenosis.

Authors:  Caitlin Bertelsen; Hagit Shoffel-Havakuk; Karla O'Dell; Michael M Johns; Lindsay S Reder
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2018-03-01       Impact factor: 6.223

Review 8.  Scar Revisions.

Authors:  Anna Skochdopole; Rami P Dibbs; Shayan M Sarrami; Robert F Dempsey
Journal:  Semin Plast Surg       Date:  2021-06-08       Impact factor: 2.314

9.  Results of a combination of bleomycin and triamcinolone acetonide in the treatment of keloids and hypertrophic scars.

Authors:  Francisco Miguel Camacho-Martínez; Elena Rodríguez Rey; Francisco Camacho Serrano; Adriana Wagner
Journal:  An Bras Dermatol       Date:  2013 May-Jun       Impact factor: 1.896

10.  Effect of botulinum toxin type a on a rat surgical wound model.

Authors:  Byung-Joo Lee; Jae-Hwi Jeong; Soo-Geun Wang; Jin-Choon Lee; Eui-Kyung Goh; Hwal-Woong Kim
Journal:  Clin Exp Otorhinolaryngol       Date:  2009-03-26       Impact factor: 3.372

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