Literature DB >> 17036295

Substrate mimicry in an activity-based probe that targets the nitrilase family of enzymes.

Katherine T Barglow1, Benjamin F Cravatt.   

Abstract

Mesh：

Substances：

Year:  2006        PMID： 17036295     DOI： 10.1002/anie.200603187

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  6 in total

Review 1.  Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms.

Authors:  Daniel Medina-Cleghorn; Daniel K Nomura
Journal:  Chem Biol       Date:  2014-09-18

2.  Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione.

Authors:  Alessio Peracchi; Maria Veiga-da-Cunha; Tomiko Kuhara; Kenneth W Ellens; Nicole Paczia; Vincent Stroobant; Agnieszka K Seliga; Simon Marlaire; Stephane Jaisson; Guido T Bommer; Jin Sun; Kay Huebner; Carole L Linster; Arthur J L Cooper; Emile Van Schaftingen
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-03       Impact factor: 11.205

3.  Rational Regulation of Reaction Specificity of Nitrilase for Efficient Biosynthesis of 2-Chloronicotinic Acid through a Single Site Mutation.

Authors:  An-Di Dai; Xiao-Ling Tang; Zhe-Ming Wu; Jiang-Tao Tang; Ren-Chao Zheng; Yu-Guo Zheng
Journal:  Appl Environ Microbiol       Date:  2022-01-12       Impact factor: 5.005

4.  Functional proteomic and structural insights into molecular recognition in the nitrilase family enzymes.

Authors:  Katherine T Barglow; Kumar S Saikatendu; Michael H Bracey; Ruth Huey; Garrett M Morris; Arthur J Olson; Raymond C Stevens; Benjamin F Cravatt
Journal:  Biochemistry       Date:  2008-12-23       Impact factor: 3.162

5.  Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.

Authors:  Daniel A Bachovchin; Steven J Brown; Hugh Rosen; Benjamin F Cravatt
Journal:  Nat Biotechnol       Date:  2009-03-29       Impact factor: 54.908

6.  A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway.

Authors:  Sonnhild Mittag; Tomas Valenta; Jörg Weiske; Laura Bloch; Susanne Klingel; Dietmar Gradl; Franziska Wetzel; Yuan Chen; Iver Petersen; Konrad Basler; Otmar Huber
Journal:  Cell Discov       Date:  2016-01-05       Impact factor: 10.849
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.