Literature DB >> 17036105

Synthesis and anticancer activity studies of alpha-aminoalkylated conjugated nitroalkenes.

Namrata Rastogi1, Renu Mohan, Dulal Panda, Shaikh M Mobin, Irishi N N Namboothiri.   

Abstract

Novel alpha-aminoalkylated conjugated nitroalkenes which inhibit human cervical cancer (HeLa) cell proliferation by binding to tubulin were synthesized by imidazole/LiCl-mediated reaction of conjugated nitroalkenes with N-tosylimines.

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Year:  2006        PMID： 17036105     DOI： 10.1039/b607537a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

1.  (E)-2-(2-Nitro-ethen-yl)furan.

Authors:  Pedro Valerga; M Carmen Puerta; Zenaida Rodríguez Negrín; Nilo Castañedo Cancio; Miguel Palma Lovillo
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-07-25

2.  Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: An efficient route for the synthesis of stereodefined allylic amines.

Authors:  Kebin Mao; Guoqin Fan; Yuanhong Liu; Shi Li; Xu You; Dan Liu
Journal:  Beilstein J Org Chem       Date:  2013-03-27       Impact factor: 2.883
  2 in total

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