| Literature DB >> 17035014 |
Subhendu Sekhar Bag1, Yoshio Saito, Kazuo Hanawa, Satoshi Kodate, Isamu Suzuka, Isao Saito.
Abstract
Fluorescence response upon hybridization of perylene labeled oligonucleotide probes depends on the microenvironment experienced by the perylene fluorophore. In mismatched duplex ((Per)U-C), enhanced fluorescence was observed while in matched duplex ((Per)U-A) fluorescence intensity decreased considerably. This observation will be a promising research effort in giving rise to a new powerful tool in detection of SNP.Entities:
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Year: 2006 PMID： 17035014 DOI： 10.1016/j.bmcl.2006.09.039
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823