Literature DB >> 17034088

In vivo molecular probing of cellular compartments with gold nanoparticles and nanoaggregates.

Janina Kneipp1, Harald Kneipp, Margaret McLaughlin, Dennis Brown, Katrin Kneipp.   

Abstract

Surface-enhanced Raman (SERS) signatures were measured from single living cells at different times after the uptake of gold nanoparticles. The spectra are indicative of chemical changes in the environment of the nanostructures over time. The increase of the SERS signal strength and parallel TEM studies indicate the formation of nanoaggregates providing optimum SERS enhancement for ultrasensitive probing inside the endosomal compartment. The results have implications for medical and biotechnology applications of SERS nanosensors in cells.

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Year:  2006        PMID: 17034088     DOI: 10.1021/nl061517x

Source DB:  PubMed          Journal:  Nano Lett        ISSN: 1530-6984            Impact factor:   11.189


  57 in total

1.  Dispersion and stability optimization of TiO2 nanoparticles in cell culture media.

Authors:  Zhaoxia Ji; Xue Jin; Saji George; Tian Xia; Huan Meng; Xiang Wang; Elizabeth Suarez; Haiyuan Zhang; Eric M V Hoek; Hilary Godwin; André E Nel; Jeffrey I Zink
Journal:  Environ Sci Technol       Date:  2010-10-01       Impact factor: 9.028

Review 2.  Surface-enhanced Raman scattering biomedical applications of plasmonic colloidal particles.

Authors:  Sara Abalde-Cela; Paula Aldeanueva-Potel; Cintia Mateo-Mateo; Laura Rodríguez-Lorenzo; Ramón A Alvarez-Puebla; Luis M Liz-Marzán
Journal:  J R Soc Interface       Date:  2010-05-12       Impact factor: 4.118

3.  SERS-Coded Gold Nanorods as a Multifunctional Platform for Densely Multiplexed Near-Infrared Imaging and Photothermal Heating.

Authors:  Geoffrey von Maltzahn; Andrea Centrone; Ji-Ho Park; Renuka Ramanathan; Michael J Sailor; T Alan Hatton; Sangeeta N Bhatia
Journal:  Adv Mater       Date:  2009-04-20       Impact factor: 30.849

4.  High resolution live cell Raman imaging using subcellular organelle-targeting SERS-sensitive gold nanoparticles with highly narrow intra-nanogap.

Authors:  Jeon Woong Kang; Peter T C So; Ramachandra R Dasari; Dong-Kwon Lim
Journal:  Nano Lett       Date:  2015-02-11       Impact factor: 11.189

5.  Electrokinetic trapping and surface enhanced Raman scattering detection of biomolecules using optofluidic device integrated with a microneedles array.

Authors:  Yu-Luen Deng; Yi-Je Juang
Journal:  Biomicrofluidics       Date:  2013-02-21       Impact factor: 2.800

6.  Highly uniform and reproducible surface-enhanced Raman scattering from DNA-tailorable nanoparticles with 1-nm interior gap.

Authors:  Dong-Kwon Lim; Ki-Seok Jeon; Jae-Ho Hwang; Hyoki Kim; Sunghoon Kwon; Yung Doug Suh; Jwa-Min Nam
Journal:  Nat Nanotechnol       Date:  2011-05-29       Impact factor: 39.213

Review 7.  Gold Nanoparticles for In Vitro Diagnostics.

Authors:  Wen Zhou; Xia Gao; Dingbin Liu; Xiaoyuan Chen
Journal:  Chem Rev       Date:  2015-06-26       Impact factor: 60.622

8.  Imaging of PD-L1 in single cancer cells by SERS-based hyperspectral analysis.

Authors:  Wei Zhang; Jake S Rhodes; Kevin R Moon; Beatrice S Knudsen; Linda Nokolova; Anhong Zhou
Journal:  Biomed Opt Express       Date:  2020-10-08       Impact factor: 3.732

9.  A two-dimensional fingerprint nanoprobe based on black phosphorus for bio-SERS analysis and chemo-photothermal therapy.

Authors:  Zhiming Liu; Haolin Chen; Yali Jia; Wen Zhang; Henan Zhao; Wendong Fan; Wolun Zhang; Huiqing Zhong; Yirong Ni; Zhouyi Guo
Journal:  Nanoscale       Date:  2018-10-02       Impact factor: 7.790

10.  Molecular imaging with surface-enhanced Raman spectroscopy nanoparticle reporters.

Authors:  Jesse V Jokerst; Christoph Pohling; Sanjiv S Gambhir
Journal:  MRS Bull       Date:  2013-08       Impact factor: 6.578

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