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Literature DB >> 30277241

A two-dimensional fingerprint nanoprobe based on black phosphorus for bio-SERS analysis and chemo-photothermal therapy.

Zhiming Liu¹, Haolin Chen, Yali Jia, Wen Zhang, Henan Zhao, Wendong Fan, Wolun Zhang, Huiqing Zhong, Yirong Ni, Zhouyi Guo.

Abstract

Flake-shaped nanohybrids based on black phosphorus (BP) have been developed as multifunctional theranostic nanoplatforms for drug delivery, phototherapy and bioimaging. In this work, we report a facile strategy for fabrication of black phosphorus-Au nanoparticle hybrids (BP-AuNPs), which reveal an extraordinary near-infrared (NIR) photothermal transduction efficiency and drug delivery capacity. The applications of the nanocomposites as therapeutic agents for high-performance chemo-photothermal tumor therapy are accomplished in vitro and in vivo. BP-AuNPs also exhibit wonderful surface-enhanced Raman scattering (SERS) activity under NIR laser excitation with a low Raman background, allowing BP-AuNPs to be used as a promising two-dimensional (2D) fingerprint nanoprobe for bio-SERS analysis. The cellular component identification and label-free live-cell bioimaging based on this type of 2D SERS substrate are generally investigated, which open up promising new perspectives in nanomedicine, including diagnosis, imaging and therapy.

Entities: CellLine Chemical Disease Gene Species

Mesh：

Substances：
Molecular Probes
Gold

Year: 2018 PMID： 30277241 PMCID： PMC6234316 DOI： 10.1039/c8nr05300f

Source DB: PubMed Journal: Nanoscale ISSN： 2040-3364 Impact factor: 7.790

43 in total

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Journal: Proc Natl Acad Sci U S A Date: 2018-01-02 Impact factor: 11.205

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8. Ultrathin Black Phosphorus Nanosheets for Efficient Singlet Oxygen Generation.

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Journal: Nat Commun Date: 2016-09-30 Impact factor: 14.919

7 in total

Review 1. Current Advances in Black Phosphorus-Based Drug Delivery Systems for Cancer Therapy.

Authors: Wenxin Liu; Alideertu Dong; Bing Wang; Han Zhang
Journal: Adv Sci (Weinh) Date: 2021-01-15 Impact factor: 16.806

2. Present and Future of Surface-Enhanced Raman Scattering.

Authors: Judith Langer; Dorleta Jimenez de Aberasturi; Javier Aizpurua; Ramon A Alvarez-Puebla; Baptiste Auguié; Jeremy J Baumberg; Guillermo C Bazan; Steven E J Bell; Anja Boisen; Alexandre G Brolo; Jaebum Choo; Dana Cialla-May; Volker Deckert; Laura Fabris; Karen Faulds; F Javier García de Abajo; Royston Goodacre; Duncan Graham; Amanda J Haes; Christy L Haynes; Christian Huck; Tamitake Itoh; Mikael Käll; Janina Kneipp; Nicholas A Kotov; Hua Kuang; Eric C Le Ru; Hiang Kwee Lee; Jian-Feng Li; Xing Yi Ling; Stefan A Maier; Thomas Mayerhöfer; Martin Moskovits; Kei Murakoshi; Jwa-Min Nam; Shuming Nie; Yukihiro Ozaki; Isabel Pastoriza-Santos; Jorge Perez-Juste; Juergen Popp; Annemarie Pucci; Stephanie Reich; Bin Ren; George C Schatz; Timur Shegai; Sebastian Schlücker; Li-Lin Tay; K George Thomas; Zhong-Qun Tian; Richard P Van Duyne; Tuan Vo-Dinh; Yue Wang; Katherine A Willets; Chuanlai Xu; Hongxing Xu; Yikai Xu; Yuko S Yamamoto; Bing Zhao; Luis M Liz-Marzán
Journal: ACS Nano Date: 2019-10-08 Impact factor: 15.881