Literature DB >> 17028275

Heme biosynthesis in Methanosarcina barkeri via a pathway involving two methylation reactions.

Bärbel Buchenau1, Jörg Kahnt, Ilka U Heinemann, Dieter Jahn, Rudolf K Thauer.   

Abstract

The methanogenic archaeon Methanosarcina barkeri synthesizes protoheme via precorrin-2, which is formed from uroporphyrinogen III in two consecutive methylation reactions utilizing S-adenosyl-L-methionine. The existence of this pathway, previously exclusively found in the sulfate-reducing delta-proteobacterium Desulfovibrio vulgaris, was demonstrated for M. barkeri via the incorporation of two methyl groups from methionine into protoheme.

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Year:  2006        PMID: 17028275      PMCID: PMC1698242          DOI: 10.1128/JB.01349-06

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  17 in total

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Review 3.  Prokaryotic Heme Biosynthesis: Multiple Pathways to a Common Essential Product.

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10.  The alternative route to heme in the methanogenic archaeon Methanosarcina barkeri.

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