| Literature DB >> 17026078 |
Martin Hunter1, Vadim Backman, Gabriel Popescu, Maxim Kalashnikov, Charles W Boone, Adam Wax, Venkatesh Gopal, Kamran Badizadegan, Gary D Stoner, Michael S Feld.
Abstract
Light scattered from biological tissues can exhibit an inverse power law spectral component. We develop a model based on the Born approximation and von Karman (self-affine) spatial correlation of submicron tissue refractive index to account for this. The model is applied to light scattering spectra obtained from excised esophagi of normal and carcinogen-treated rats. Power law exponents used to fit dysplastic tissue site spectra are significantly smaller than those from normal sites, indicating that changes in tissue self-affinity can serve as a potential biomarker for precancer.Entities:
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Year: 2006 PMID： 17026078 DOI： 10.1103/PhysRevLett.97.138102
Source DB: PubMed Journal: Phys Rev Lett ISSN： 0031-9007 Impact factor: 9.161