Literature DB >> 17016229

Surgical management of cervical spine osteoblastomas.

Vincenzo Denaro1, Luca Denaro, Rocco Papalia, Andrea Marinozzi, Alberto Di Martino.   

Abstract

The treatment of cervical spine osteoblastomas requires complex therapeutic and reconstructive strategies depending on the tumor's location, local aggressiveness, and proximity to the surrounding neurovascular structures. Despite careful removal, lesions recur in as much as 10% of patients. Preoperative embolization is useful to minimize intraoperative bleeding and decrease the relapse of vascular tumors, but its role in osteoblastoma surgery is yet to be defined. We asked whether preoperative embolization with marginal resection would lead to osteoblastoma recurrence, and whether marginal excision with reconstruction would improve neurologic symptoms. We retrospectively analyzed a consecutive series of patients with cervical spine osteoblastoma, treated by one surgeon with a combined approach of preoperative embolization, marginal excision, and spinal reconstruction. One of nine patients presented with a monoradiculopathy, whereas only two patients presented with symptomatic spinal cord compression. At followup, all patients showed neurologic improvement, no tumor relapse, and adequate bony healing. Followup imaging studies showed cervical alignment was maintained. Although we report only a small uncontrolled cohort, the data suggest preoperative embolization and a tumor-free margin are consistent with a prolonged disease-free interval or complete tumor eradication.

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Year:  2007        PMID: 17016229     DOI: 10.1097/01.blo.0000238846.34047.d9

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  8 in total

1.  Expert's Comment concerning Grand Rounds case entitled "Diagnosis and treatment of a C2-osteoblastoma encompassing the vertebral artery" (by Stavros I. Stavridis, Andreas Pingel, Klaus John Schnake and Frank Kandziora).

Authors:  Osmar J S Moraes
Journal:  Eur Spine J       Date:  2013-11-07       Impact factor: 3.134

Review 2.  Multidisciplinary management of primary tumors of the vertebral column.

Authors:  Wesley Hsu; Thomas A Kosztowski; Hasan A Zaidi; Michael Dorsi; Ziya L Gokaslan; Jean-Paul Wolinsky
Journal:  Curr Treat Options Oncol       Date:  2009-06-23

3.  Diagnosis and treatment of a C2-osteoblastoma encompassing the vertebral artery.

Authors:  Stavros I Stavridis; Andreas Pingel; Klaus John Schnake; Frank Kandziora
Journal:  Eur Spine J       Date:  2013-07-10       Impact factor: 3.134

4.  Embolization of musculoskeletal bone tumors.

Authors:  Richard J T Owen
Journal:  Semin Intervent Radiol       Date:  2010-06       Impact factor: 1.513

5.  Patients with cervical metastasis and neoplastic pachymeningitis are less likely to improve neurologically after surgery.

Authors:  Vincenzo Denaro; Alberto Di Martino; Rocco Papalia; Luca Denaro
Journal:  Clin Orthop Relat Res       Date:  2011-03       Impact factor: 4.176

Review 6.  Treatment of osteoblastoma at C7: a multidisciplinary approach. A case report and review of the literature.

Authors:  Amer Samdani; Andrew Torre-Healy; Dean Chou; Anne Marie Cahill; Phillip B Storm
Journal:  Eur Spine J       Date:  2008-10-07       Impact factor: 3.134

7.  Pseudomalignant osteoblastoma of the odontoid process.

Authors:  Pedro Fernandes; Joaquim Soares do Brito; Adília Costa; Jacinto Monteiro
Journal:  Eur Spine J       Date:  2018-01-29       Impact factor: 3.134

8.  Removal of osteoblastoma of the talar neck using standard anterior ankle Arthroscopy:A case report.

Authors:  Xiao-Jun Duan; Liu Yang
Journal:  Int J Surg Case Rep       Date:  2016-03-14
  8 in total

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