Literature DB >> 23838701

Diagnosis and treatment of a C2-osteoblastoma encompassing the vertebral artery.

Stavros I Stavridis1, Andreas Pingel, Klaus John Schnake, Frank Kandziora.   

Abstract

INTRODUCTION: Osteoblastoma is a rare, benign bone tumor that accounts for approximately 1% of all primary bone tumors and 5% of spinal tumors, mostly arising within the posterior elements of the spine within the second and third decades of life. Nonspecific initial symptoms mainly neck or back pain and stiffness of the spine remain often undiagnosed and the destructive nature of the expanding tumor can cause even neurological deficits. CT and MRI scans constitute the basic imaging modalities employed in diagnosis and preoperative planning with the former delineating the location and osseous involvement of the mass and the latter providing appreciation of the effect on soft tissues and neural elements.
MATERIALS AND METHODS: In our case a 23-year-old male presented with persisting head and neck pain, after being involved in a car collision a month ago. Although the initial diagnostic imaging, including plain X-rays and MRI scan failed to reveal any pathological findings, the persistence of the symptoms led to repeating imaging (CT and MRI) that showed the existence of a benign osseous tumor of the C2 lamina that was destructing the surrounding osseous structures and encompassing the right vertebral artery. The suspicion of an osteoblastoma was raised and the decision for surgical removal of the tumor was made for treating the persistent symptoms and preventing a possible neurological deficit or vascular lesion. A marginal tumor resection was performed through a posterior approach, followed by an anterior instrumented fusion. Histological examination confirmed the diagnosis of an osteoblastoma.
RESULTS: The recovery of the patient was uneventful and a significant symptom subsidence was reported following surgery. Eighteen months postoperatively the patient remains pain free without any indications for tumor recurrence.
CONCLUSION: This case delineates the difficulties in diagnosing this tumor, as well as the challenges and problems encountered in its surgical management, and also the favorable prognosis when adequately treated.

Entities:  

Mesh:

Year:  2013        PMID: 23838701      PMCID: PMC3886513          DOI: 10.1007/s00586-013-2875-5

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  19 in total

1.  Osteoid osteoma and osteoblastoma of the spine. Factors associated with the presence of scoliosis.

Authors:  A Saifuddin; J White; Z Sherazi; M I Shaikh; C Natali; A O Ransford
Journal:  Spine (Phila Pa 1976)       Date:  1998-01-01       Impact factor: 3.468

Review 2.  Osteoblastoma of dorsal spine: a case report.

Authors:  P Tripathy; S Sarkar; B Maiti
Journal:  Neurol India       Date:  1999-12       Impact factor: 2.117

3.  The spectrum of osteoblastoma.

Authors:  R A McLeod; D C Dahlin; J W Beabout
Journal:  AJR Am J Roentgenol       Date:  1976-02       Impact factor: 3.959

4.  The diagnostic accuracy of MRI versus CT imaging for osteoid osteoma in children.

Authors:  Harish S Hosalkar; Sumeet Garg; Leslie Moroz; Avrum Pollack; John P Dormans
Journal:  Clin Orthop Relat Res       Date:  2005-04       Impact factor: 4.176

5.  Osteoblastoma of the spine.

Authors:  S Boriani; R Capanna; D Donati; A Levine; P Picci; R Savini
Journal:  Clin Orthop Relat Res       Date:  1992-05       Impact factor: 4.176

6.  Osteoid osteoma and osteoblastoma of the spine: experiences with 22 patients.

Authors:  Toshifumi Ozaki; Ulf Liljenqvist; Axel Hillmann; Henry Halm; Norbert Lindner; Georg Gosheger; Winfried Winkelmann
Journal:  Clin Orthop Relat Res       Date:  2002-04       Impact factor: 4.176

7.  Osteoblastoma of the spine. A review of 75 cases.

Authors:  O Nemoto; R P Moser; B E Van Dam; J Aoki; F W Gilkey
Journal:  Spine (Phila Pa 1976)       Date:  1990-12       Impact factor: 3.468

Review 8.  Osteoid osteomas and osteoblastomas of the spine.

Authors:  Mehmet Zileli; Sedat Cagli; Gülcin Basdemir; Yusuf Ersahin
Journal:  Neurosurg Focus       Date:  2003-11-15       Impact factor: 4.047

9.  Differential diagnosis of benign tumors and tumor-like lesions in the spine. Own cases and review of the literature.

Authors:  S M Knoeller; M Uhl; C-P Adler; G W Herget
Journal:  Neoplasma       Date:  2004       Impact factor: 2.575

10.  Osteoblastoma: clinicopathologic study of 306 cases.

Authors:  D R Lucas; K K Unni; R A McLeod; M I O'Connor; F H Sim
Journal:  Hum Pathol       Date:  1994-02       Impact factor: 3.466

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  6 in total

1.  Cervical osteoblastoma resection and posterior fusion.

Authors:  Yann Philippe Charles; Sébastien Schuller; Gergi Sfeir; Jean-Paul Steib
Journal:  Eur Spine J       Date:  2014-03       Impact factor: 3.134

2.  Expert's Comment concerning Grand Rounds case entitled "Diagnosis and treatment of a C2-osteoblastoma encompassing the vertebral artery" (by Stavros I. Stavridis, Andreas Pingel, Klaus John Schnake and Frank Kandziora).

Authors:  Osmar J S Moraes
Journal:  Eur Spine J       Date:  2013-11-07       Impact factor: 3.134

3.  Aggressive osteoblastoma of the cervical spine involving the canal and vertebral artery: a case report.

Authors:  Kei Ando; Shiro Imagama; Kazuyoshi Kobayashi; Yoshihiro Nishida; Naoki Ishiguro
Journal:  Eur Spine J       Date:  2016-12-15       Impact factor: 3.134

Review 4.  Surgical management of an osteoblastoma involving the entire C2 vertebra and a review of literature.

Authors:  Kemal Koc; Mustafa Kemal Ilik
Journal:  Eur Spine J       Date:  2016-02-15       Impact factor: 3.134

5.  The one-in-all diagnostic value of 99mTc-MDP bone scan combining with single-photon emission tomography (SPECT)/CT imaging in spinal osteoblastoma.

Authors:  Wenhui Ma; Zhiyong Quan; Jing Wang; Xiangdong Li; Guoquan Li
Journal:  J Orthop Surg Res       Date:  2020-05-24       Impact factor: 2.359

6.  Anterior Reconstruction of C2-C3 Bodies in a 6-Year-Old Patient with a Huge Osteoblastoma: A Novel Technique.

Authors:  Ali Haghnegahdar; Mahsa Sedighi
Journal:  Global Spine J       Date:  2015-05-06
  6 in total

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