Literature DB >> 17015628

Efficacy of caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans.

J C Bowman1, G K Abruzzo, A M Flattery, C J Gill, E J Hickey, M J Hsu, J Nielsen Kahn, P A Liberator, A S Misura, B A Pelak, T C Wang, C M Douglas.   

Abstract

The echinocandin caspofungin is a potent inhibitor of the activity of 1,3-beta-D-glucan synthase from Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans. In murine models of disseminated infection, caspofungin prolonged survival and reduced the kidney fungal burden. Caspofungin was at least as effective as amphotericin B against these filamentous fungi in vivo.

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Year:  2006        PMID： 17015628      PMCID： PMC1693977          DOI： 10.1128/AAC.00485-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  29 in total

Review 1.  Fungal beta(1,3)-D-glucan synthesis.

Authors:  C M Douglas
Journal:  Med Mycol       Date:  2001       Impact factor: 4.076

2.  Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients.

Authors:  Kieren A Marr; Rachel A Carter; Fulvio Crippa; Anna Wald; Lawrence Corey
Journal:  Clin Infect Dis       Date:  2002-02-26       Impact factor: 9.079

3.  Caspofungin susceptibility in Aspergillus and non-Aspergillus molds: inhibition of glucan synthase and reduction of beta-D-1,3 glucan levels in culture.

Authors:  Jennifer Nielsen Kahn; Ming-Jo Hsu; Fred Racine; Robert Giacobbe; Mary Motyl
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

4.  Antifungal efficacy of caspofungin (MK-0991) in experimental pulmonary aspergillosis in persistently neutropenic rabbits: pharmacokinetics, drug disposition, and relationship to galactomannan antigenemia.

Authors:  Ruta Petraitiene; Vidmantas Petraitis; Andreas H Groll; Tin Sein; Robert L Schaufele; Andrea Francesconi; John Bacher; Nilo A Avila; Thomas J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

5.  Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice.

Authors:  G K Abruzzo; C J Gill; A M Flattery; L Kong; C Leighton; J G Smith; V B Pikounis; K Bartizal; H Rosen
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

6.  Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate.

Authors:  J C Bowman; G K Abruzzo; J W Anderson; A M Flattery; C J Gill; V B Pikounis; D M Schmatz; P A Liberator; C M Douglas
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

Review 7.  Aspergillosis case-fatality rate: systematic review of the literature.

Authors:  S J Lin; J Schranz; S M Teutsch
Journal:  Clin Infect Dis       Date:  2001-01-26       Impact factor: 9.079

8.  Development and validation of a quantitative real-time PCR assay using fluorescence resonance energy transfer technology for detection of Aspergillus fumigatus in experimental invasive pulmonary aspergillosis.

Authors:  Cathal E O'Sullivan; Miki Kasai; Andrea Francesconi; Vidmantas Petraitis; Ruta Petraitiene; Amy M Kelaher; Alia A Sarafandi; Thomas J Walsh
Journal:  J Clin Microbiol       Date:  2003-12       Impact factor: 5.948

Review 9.  Invasive Aspergillus infections in hematologic malignancy patients.

Authors:  Sofia Perea; Thomas F Patterson
Journal:  Semin Respir Infect       Date:  2002-06

10.  Evaluation of broth microdilution testing parameters and agar diffusion Etest procedure for testing susceptibilities of Aspergillus spp. to caspofungin acetate (MK-0991).

Authors:  Ana Espinel-Ingroff
Journal:  J Clin Microbiol       Date:  2003-01       Impact factor: 5.948
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  13 in total

Review 1.  Resistance to echinocandin-class antifungal drugs.

Authors:  David S Perlin
Journal:  Drug Resist Updat       Date:  2007-06-13       Impact factor: 18.500

2.  Chitin synthases with a myosin motor-like domain control the resistance of Aspergillus fumigatus to echinocandins.

Authors:  Cristina Jiménez-Ortigosa; Vishukumar Aimanianda; Laetitia Muszkieta; Isabelle Mouyna; David Alsteens; Stéphane Pire; Remi Beau; Sven Krappmann; Anne Beauvais; Yves F Dufrêne; César Roncero; Jean-Paul Latgé
Journal:  Antimicrob Agents Chemother       Date:  2012-09-10       Impact factor: 5.191

Review 3.  Echinocandin resistance, susceptibility testing and prophylaxis: implications for patient management.

Authors:  David S Perlin
Journal:  Drugs       Date:  2014-09       Impact factor: 9.546

4.  Concentration-dependent effects of caspofungin on the metabolic activity of Aspergillus species.

Authors:  Charalampos Antachopoulos; Joseph Meletiadis; Tin Sein; Emmanuel Roilides; Thomas J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2006-12-04       Impact factor: 5.191

Review 5.  Echinocandin antifungal drugs in fungal infections: a comparison.

Authors:  Sharon C-A Chen; Monica A Slavin; Tania C Sorrell
Journal:  Drugs       Date:  2011-01-01       Impact factor: 9.546

6.  Differences in efficacy and cytokine profiles following echinocandin or liposomal amphotericin B monotherapy or combination therapy for murine pulmonary or systemic Aspergillus flavus infections.

Authors:  J A Olson; J Schwartz; D Hahka; A George; R T Proffitt; J P Adler-Moore
Journal:  Antimicrob Agents Chemother       Date:  2011-10-03       Impact factor: 5.191

7.  A Second-Generation Fungerp Analog, SCY-247, Shows Potent In Vitro Activity against Candida auris and Other Clinically Relevant Fungal Isolates.

Authors:  Sherman Chu; Lisa Long; Rania Sherif; Thomas S McCormick; Katyna Borroto-Esoda; Stephen Barat; Mahmoud A Ghannoum
Journal:  Antimicrob Agents Chemother       Date:  2021-02-17       Impact factor: 5.191

Review 8.  Mechanisms of echinocandin antifungal drug resistance.

Authors:  David S Perlin
Journal:  Ann N Y Acad Sci       Date:  2015-07-17       Impact factor: 5.691

9.  Spondylodiscitis Due to Aspergillus terreus in an Immunocompetent Host: Case Report and Literature Review.

Authors:  Pauline Comacle; Yohann Le Govic; Cyril Hoche-Delchet; Jeremy Sandrini; Claire Aguilar; Benjamin Bouyer; Sophie Blanchi; Pascale Penn
Journal:  Mycopathologia       Date:  2016-04-02       Impact factor: 2.574

10.  Comparative in vitro pharmacodynamics of caspofungin, micafungin, and anidulafungin against germinated and nongerminated Aspergillus conidia.

Authors:  Charalampos Antachopoulos; Joseph Meletiadis; Tin Sein; Emmanuel Roilides; Thomas J Walsh
Journal:  Antimicrob Agents Chemother       Date:  2007-10-15       Impact factor: 5.191
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