| Literature DB >> 17015454 |
Uros Skaleric1, Boris Gaspirc, Nancy McCartney-Francis, Andrej Masera, Sharon M Wahl.
Abstract
Abnormal nitric oxide (NO) synthesis has been implicated in the pathogenesis of both periodontal disease and diabetes mellitus. In diabetic patients, increased inducible NO synthase in inflamed gingiva correlated with NO in gingival crevicular fluid. Although increased NO reflected more-severe inflammation, it was associated with reductions in CFU of Prevotella intermedia, a major periodontopathogen, highlighting dual roles for NO.Entities:
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Year: 2006 PMID: 17015454 PMCID: PMC1698046 DOI: 10.1128/IAI.00071-06
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441