Literature DB >> 17012501

Developing capacity to protect human research subjects in a post-conflict, resource-constrained setting: procedures and prospects.

S B Kennedy1, A O Harris, E Oudemans, L Young, J Kollie, E S Nelson, R A Nisbett, C Morris, N Bartee, E George-Williams, J Jones.   

Abstract

The capacity-building strategy used by a US-based research organisation, the Pacific Institute for Research and Evaluation (PIRE), to strengthen the system for the protection of human research subjects and the infrastructure of its international collaborating partner, the University of Liberia, are discussed. To conduct the much-needed biomedical and social science-based research-related activities in the future, this partnership is expected by PIRE to gradually evolve over time to strengthen the capacity of the local investigators and administrators of the University of Liberia. Accordingly, a unique opportunity to share technology and resources with a post-conflict, resource-constrained country is created by this partnership. This capacity-building model to strengthen the protection of human subjects in research can also be replicated in similar resource-constrained international settings and, accordingly, our experiences and limitations are shared in this paper.

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Year:  2006        PMID: 17012501      PMCID: PMC1994516          DOI: 10.1136/jme.2005.014472

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  16 in total

1.  What makes clinical research in developing countries ethical? The benchmarks of ethical research.

Authors:  Ezekiel J Emanuel; David Wendler; Jack Killen; Christine Grady
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2.  Community permission for medical research in developing countries.

Authors:  Dapa A Diallo; Ogobara K Doumbo; Christopher V Plowe; Thomas E Wellems; Ezekiel J Emanuel; Samia A Hurst
Journal:  Clin Infect Dis       Date:  2005-06-07       Impact factor: 9.079

3.  Unethical trials of interventions to reduce perinatal transmission of the human immunodeficiency virus in developing countries.

Authors:  P Lurie; S M Wolfe
Journal:  N Engl J Med       Date:  1997-09-18       Impact factor: 91.245

4.  Ethical complexities of conducting research in developing countries.

Authors:  H Varmus; D Satcher
Journal:  N Engl J Med       Date:  1997-10-02       Impact factor: 91.245

Review 5.  The medical ethos and social responsibility in clinical medicine.

Authors:  C K Francis
Journal:  J Natl Med Assoc       Date:  2001-05       Impact factor: 1.798

6.  Ethical imperialism? Ethics in international collaborative clinical research.

Authors:  M Angell
Journal:  N Engl J Med       Date:  1988-10-20       Impact factor: 91.245

7.  Randomised placebo-controlled trials and HIV-infected pregnant women in developing countries. Ethical imperialism or unethical exploitation?

Authors:  P de Zulueta
Journal:  Bioethics       Date:  2001-08       Impact factor: 1.898

8.  African Americans' views on research and the Tuskegee Syphilis Study.

Authors:  V S Freimuth; S C Quinn; S B Thomas; G Cole; E Zook; T Duncan
Journal:  Soc Sci Med       Date:  2001-03       Impact factor: 4.634

9.  The complex challenge of HIV/AIDS care: a global perspective: an update from XIIIth International AIDS Conference.

Authors:  J R Roberts
Journal:  Clin Excell Nurse Pract       Date:  2000-11

10.  Evaluation of HIV/AIDS prevention resources in Liberia: strategy and implications.

Authors:  Stephen B Kennedy; Knowlton Johnson; Albert O Harris; Adams Lincoln; William Neace; David Collins
Journal:  AIDS Patient Care STDS       Date:  2004-03       Impact factor: 5.078

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  3 in total

1.  Condom social marketing program to prevent HIV/AIDS in post-conflict Liberia.

Authors:  A O Harris; S Jubwe; S B Kennedy; C H Taylor; R B Martin; E M Bee; O S Perry; M T Massaquoi; D V Woods; E M Barbu
Journal:  Afr Health Sci       Date:  2011-08       Impact factor: 0.927

2.  HIV/STD risk behaviors among in-school adolescents in post-conflict Liberia.

Authors:  Stephen B Kennedy; Katharine A Atwood; Albert O Harris; Curtis H Taylor; Mawen E Gobeh; Monica Quaqua; Daisajou V Woods; Ernree M Bee; Matthew Warlonfa
Journal:  J Assoc Nurses AIDS Care       Date:  2011-09-15       Impact factor: 1.354

3.  Composition, training needs and independence of ethics review committees across Africa: are the gate-keepers rising to the emerging challenges?

Authors:  A Nyika; W Kilama; R Chilengi; G Tangwa; P Tindana; P Ndebele; J Ikingura
Journal:  J Med Ethics       Date:  2009-03       Impact factor: 2.903

  3 in total

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