| Literature DB >> 1701162 |
M Mousli1, C Bronner, J Bockaert, B Rouot, Y Landry.
Abstract
Pretreatment of purified calf brain G proteins with activated pertussis toxin or antibodies raised against the C-terminus of their alpha subunits prevented the increase in GTPase activity induced by substance P, compound 48/80 and mastoparan. These results suggest that these mast cell secretagogues activate G proteins directly via an interaction with the C-terminus of alpha subunits of G proteins by mimicking the agonist-liganded receptors.Entities:
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Year: 1990 PMID： 1701162 DOI： 10.1016/0165-2478(90)90207-7
Source DB: PubMed Journal: Immunol Lett ISSN： 0165-2478 Impact factor: 3.685