Literature DB >> 16990130

Brain evolution and uniqueness in the human genome.

Jordan P Amadio1, Christopher A Walsh.   

Abstract

Despite an ever-expanding database of sequenced mammalian genomes to be mined for clues, the emergence of the unique human brain remains an evolutionary enigma. In their new study, trawl the human genome and those of other mammals in search of short conserved DNA elements that show extremely rapid evolution only in humans. As they report in a recent issue of Nature, their scan yielded a gene for a novel noncoding RNA that adopts a human-specific structure and may regulate neurodevelopment.

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Year:  2006        PMID： 16990130     DOI： 10.1016/j.cell.2006.09.007

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  6 in total

1.  Scientific Ethics: A New Approach.

Authors:  Marcello Menapace
Journal:  Sci Eng Ethics       Date:  2018-06-04       Impact factor: 3.525

2.  Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sjögren's syndrome.

Authors:  Sergio A Jimenez; Sonsoles Piera-Velazquez
Journal:  Autoimmun Rev       Date:  2013-05-15       Impact factor: 9.754

3.  Genetic tools and algorithms for gene discovery in major congenital anomalies.

Authors:  Patricia K Donahoe; Kristin M Noonan; Kasper Lage
Journal:  Birth Defects Res A Clin Mol Teratol       Date:  2009-01

4.  Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling.

Authors:  Masato Yano; Yoshika Hayakawa-Yano; Aldo Mele; Robert B Darnell
Journal:  Neuron       Date:  2010-06-24       Impact factor: 17.173

5.  Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.

Authors:  Nelle Lambert; Marie-Alexandra Lambot; Angéline Bilheu; Valérie Albert; Yvon Englert; Frédérick Libert; Jean-Christophe Noel; Christos Sotiriou; Alisha K Holloway; Katherine S Pollard; Vincent Detours; Pierre Vanderhaeghen
Journal:  PLoS One       Date:  2011-03-18       Impact factor: 3.240

6.  Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

Authors:  Ikuo K Suzuki; David Gacquer; Roxane Van Heurck; Devesh Kumar; Marta Wojno; Angéline Bilheu; Adèle Herpoel; Nelle Lambert; Julian Cheron; Franck Polleux; Vincent Detours; Pierre Vanderhaeghen
Journal:  Cell       Date:  2018-05-31       Impact factor: 41.582
  6 in total

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