Literature DB >> 16987515

A modified Plasmodium falciparum growth inhibition assay (GIA) to assess activity of plasma from malaria endemic areas.

Godfree Mlambo1, Nirbhay Kumar.   

Abstract

Plasma samples from patients undergoing treatment in malaria endemic countries often contain anti-malaria drugs, that may overstate effects of specific antibodies in growth inhibition assays (GIA). We describe a modified assay that uses drug resistant P. falciparum parasites (W2) that circumvents the requirement for dialyzing samples that may likely contain drugs such as chloroquine and sulfadoxine/pyrimethamine (SP).

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Year:  2006        PMID： 16987515     DOI： 10.1016/j.exppara.2006.08.003

Source DB:  PubMed          Journal:  Exp Parasitol        ISSN： 0014-4894            Impact factor:   2.011


  6 in total

Review 1.  Transgenic rodent Plasmodium berghei parasites as tools for assessment of functional immunogenicity and optimization of human malaria vaccines.

Authors:  Godfree Mlambo; Nirbhay Kumar
Journal:  Eukaryot Cell       Date:  2008-09-19

Review 2.  Can growth inhibition assays (GIA) predict blood-stage malaria vaccine efficacy?

Authors:  Christopher J A Duncan; Adrian V S Hill; Ruth D Ellis
Journal:  Hum Vaccin Immunother       Date:  2012-04-20       Impact factor: 3.452

3.  Impact of schistosome infection on Plasmodium falciparum Malariometric indices and immune correlates in school age children in Burma Valley, Zimbabwe.

Authors:  Davison T Sangweme; Nicholas Midzi; Sekesai Zinyowera-Mutapuri; Takafira Mduluza; Marie Diener-West; Nirbhay Kumar
Journal:  PLoS Negl Trop Dis       Date:  2010-11-09

4.  Efficient measurement of opsonising antibodies to Plasmodium falciparum merozoites.

Authors:  Danika L Hill; Emily M Eriksson; Amandine B Carmagnac; Danny W Wilson; Alan F Cowman; Diana S Hansen; Louis Schofield
Journal:  PLoS One       Date:  2012-12-26       Impact factor: 3.240

5.  Investigation of volatile organic biomarkers derived from Plasmodium falciparum in vitro.

Authors:  Rina P M Wong; Gavin R Flematti; Timothy M E Davis
Journal:  Malar J       Date:  2012-09-07       Impact factor: 2.979

6.  Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults.

Authors:  Arlene E Dent; Elke S Bergmann-Leitner; Danny W Wilson; Daniel J Tisch; Rhonda Kimmel; John Vulule; Peter Odada Sumba; James G Beeson; Evelina Angov; Ann M Moormann; James W Kazura
Journal:  PLoS One       Date:  2008-10-29       Impact factor: 3.240
  6 in total

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