Literature DB >> 16985979

Endothelial dysfunction, erectile dysfunction, and coronary heart disease: the pathophysiologic and clinical linkage.

Richard A Stein.   

Abstract

Our rapidly expanding knowledge regarding the biology of the endothelial cell and the pathophysiology of coronary heart disease (CHD) and endothelial dysfunction indicates important common factors and overlapping clinical presentations. We are, in effect, presented with a new paradigm-that of varying vascular manifestations of disease linked to the functioning of endothelial cell lining. This article reviews these areas of advancement and addresses their clinical implications regarding erectile dysfunction and CHD, as well as the role of the phosphodiesterase-5 inhibitor sildenafil.

Entities:  

Year:  2003        PMID： 16985979      PMCID： PMC1502382     

Source DB:  PubMed          Journal:  Rev Urol        ISSN： 1523-6161


  18 in total

1.  Hemodynamic effects of sildenafil in men with severe coronary artery disease.

Authors:  H C Herrmann; G Chang; B D Klugherz; P D Mahoney
Journal:  N Engl J Med       Date:  2000-06-01       Impact factor: 91.245

2.  Does severity of ischemic coronary disease correlate with erectile function?

Authors:  A Greenstein; J Chen; H Miller; H Matzkin; Y Villa; Z Braf
Journal:  Int J Impot Res       Date:  1997-09       Impact factor: 2.896

3.  Circulating cell adhesion molecules and death in patients with coronary artery disease.

Authors:  S Blankenberg; H J Rupprecht; C Bickel; D Peetz; G Hafner; L Tiret; J Meyer
Journal:  Circulation       Date:  2001-09-18       Impact factor: 29.690

Review 4.  Penile erection and cardiac risk: pathophysiologic and pharmacologic mechanisms.

Authors:  K Andersson; C Stief
Journal:  Am J Cardiol       Date:  2000-07-20       Impact factor: 2.778

5.  Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current.

Authors:  P Geelen; B Drolet; J Rail; J Bérubé; P Daleau; G Rousseau; R Cardinal; G E O'Hara; J Turgeon
Journal:  Circulation       Date:  2000-07-18       Impact factor: 29.690

Review 6.  The mutually reinforcing triad of depressive symptoms, cardiovascular disease, and erectile dysfunction.

Authors:  I Goldstein
Journal:  Am J Cardiol       Date:  2000-07-20       Impact factor: 2.778

Review 7.  Magnetic resonance imaging to identify the high-risk plaque.

Authors:  Christopher M Kramer
Journal:  Am J Cardiol       Date:  2002-11-21       Impact factor: 2.778

8.  Cardiovascular effects of sildenafil during exercise in men with known or probable coronary artery disease: a randomized crossover trial.

Authors:  Adelaide M Arruda-Olson; Douglas W Mahoney; Ajay Nehra; Marilyn Leckel; Patricia A Pellikka
Journal:  JAMA       Date:  2002-02-13       Impact factor: 56.272

9.  Cardiac electrophysiologic and hemodynamic effects of sildenafil, a PDE5 inhibitor, in anesthetized dogs.

Authors:  A Sugiyama; Y Satoh; H Shiina; A Takahara; M Yoneyama; K Hashimoto
Journal:  J Cardiovasc Pharmacol       Date:  2001-12       Impact factor: 3.105

10.  Myocardial infarction and its influence on male sexual function.

Authors:  C B Dhabuwala; A Kumar; J M Pierce
Journal:  Arch Sex Behav       Date:  1986-12
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  6 in total

1.  Increased subsequent risk of erectile dysfunction among middle and old age males with chronic osteomyelitis: a nationwide population-based cohort study.

Authors:  H-Y Wang; C-H Chao; C-L Lin; C-H Tseng; C-H Kao
Journal:  Int J Impot Res       Date:  2016-05-12       Impact factor: 2.896

Review 2.  The effect of diet on BPH, LUTS and ED.

Authors:  Mahmoud ElJalby; Dominique Thomas; Dean Elterman; Bilal Chughtai
Journal:  World J Urol       Date:  2018-11-23       Impact factor: 4.226

3.  Usefulness of serum fetuin-A level as a marker of erectile dysfunction.

Authors:  W Kandeel; W El-Shaer; A Sebaey; A A Abou-Taleb; A Fathy; B Elmohamady; A I Mansour
Journal:  Int J Impot Res       Date:  2017-04-20       Impact factor: 2.896

4.  Nocturia indicates a poor health status and increases mortality in male patients with type 2 diabetes mellitus.

Authors:  Hui-Ying Liu; Min-Shen Chung; Hung-Jen Wang; Rue-Tsuan Liu; Yao-Chi Chuang
Journal:  Int Urol Nephrol       Date:  2016-05-07       Impact factor: 2.370

5.  Early manifestation of aging-related vascular dysfunction in human penile vasculature-A potential explanation for the role of erectile dysfunction as a harbinger of systemic vascular disease.

Authors:  Mariam El Assar; Javier Angulo; Esther García-Rojo; Alejandro Sevilleja-Ortiz; Borja García-Gómez; Argentina Fernández; Alberto Sánchez-Ferrer; José M La Fuente; Javier Romero-Otero; Leocadio Rodríguez-Mañas
Journal:  Geroscience       Date:  2021-12-28       Impact factor: 7.713

6.  Restorative therapy clinical trials for erectile dysfunction: a scoping review of endpoint measures.

Authors:  Russell G Saltzman; Roei Golan; Thomas A Masterson; Aditya Sathe; Ranjith Ramasamy
Journal:  Int J Impot Res       Date:  2022-09-06       Impact factor: 2.408
  6 in total

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