| Literature DB >> 16969081 |
F Gregory Buchanan1, Raymond N DuBois.
Abstract
Arrestins were originally characterized as structural adaptor proteins which modulate the desensitization and trafficking of seven-membrane-spanning receptors. From these seminal observations a multitude of novel functions for this gene family have arisen. Here we review the recently identified roles for beta-arrestin including its nuclear function and roles in development, cellular migration, and metastasis.Mesh:
Substances:
Year: 2006 PMID: 16969081 DOI: 10.4161/cc.5.18.3212
Source DB: PubMed Journal: Cell Cycle ISSN: 1551-4005 Impact factor: 4.534