Literature DB >> 16967300

Effect of intervention promoting a reduction in antibiotic prescribing by improvement of diagnostic procedures: a prospective, before and after study in general practice.

Lars Bjerrum1, Josep M Cots, Carl Llor, Núria Molist, Anders Munck.   

Abstract

OBJECTIVE: To investigate if an intervention aimed at improving the quality of the diagnostic procedures in Spanish general practice could lower antibiotic prescribing in patients with respiratory tract infections (RTIs).
METHODS: GPs in the intervention group (n=17) registered all patients with RTIs during a 3-week period before and after the intervention. The intervention was aimed at reducing prescribing of inappropriate antibiotics for RTIs by improving the diagnostic procedures and thereby helping the GPs to distinguish between bacterial and viral infections. It consisted of courses in management of RTI according to local clinical guidelines, and included implementation of two rapid diagnostic tests (StrepA and CRP measurement). Diagnoses and prescribing of antibiotics were assessed before and after the intervention, and compared to a control group not exposed to intervention (35 GPs).
RESULTS: The intervention led to a significant reduction in antibiotic prescribing. Before the intervention 36% (29%-44%) of consultations were followed by antibiotic prescribing, after the intervention 24% (20%-29%). Antibiotic prescribing in the control group not exposed to intervention was 32% (27%-38%). The reduction was most pronounced in patients with sinusitis and lower RTIs.
CONCLUSION: Quality improvement of diagnostic procedures may lead to a reduction of antibiotic prescribing in primary health care in Spain.

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Year:  2006        PMID: 16967300     DOI: 10.1007/s00228-006-0187-y

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN: 0031-6970            Impact factor:   2.953


  19 in total

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Journal:  J Antimicrob Chemother       Date:  2000-03       Impact factor: 5.790

2.  Appropriateness of antibiotic prescriptions in community-acquired acute pediatric respiratory infections in Spanish emergency rooms.

Authors:  C Ochoa; L Inglada; J M Eiros; G Solís; A Vallano; L Guerra
Journal:  Pediatr Infect Dis J       Date:  2001-08       Impact factor: 2.129

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5.  Randomised controlled trial of CRP rapid test as a guide to treatment of respiratory infections in general practice.

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7.  Treatment of chronic obstructive pulmonary disease and its exacerbations in general practice. EOLO Group. Estudio Observacional de la Limitación Obstructiva al Flujo aEreo.

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Journal:  Respir Med       Date:  1999-03       Impact factor: 3.415

8.  Contributions of symptoms, signs, erythrocyte sedimentation rate, and C-reactive protein to a diagnosis of pneumonia in acute lower respiratory tract infection.

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9.  [The value of C-reactive protein testing in suspected lower respiratory tract infections. A study from general practice on the effect of a rapid test on antibiotic research and course of the disease in adults].

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Review 2.  Effectiveness of physician-targeted interventions to improve antibiotic use for respiratory tract infections.

Authors:  Alike W van der Velden; Eefje J Pijpers; Marijke M Kuyvenhoven; Sarah K G Tonkin-Crine; Paul Little; Theo J M Verheij
Journal:  Br J Gen Pract       Date:  2012-12       Impact factor: 5.386

3.  Diagnosis and management of acute pharyngitis in a paediatric population: a cost-effectiveness analysis.

Authors:  Carolina Giraldez-Garcia; Beltran Rubio; Jose F Gallegos-Braun; Iñaki Imaz; Jesus Gonzalez-Enriquez; Antonio Sarria-Santamera
Journal:  Eur J Pediatr       Date:  2011-02-11       Impact factor: 3.183

4.  Revisiting current "barefoot doctors" in border areas of China: system of services, financial issue and clinical practice prior to introducing integrated management of childhood illness (IMCI).

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Journal:  BMC Public Health       Date:  2012-08-07       Impact factor: 3.295

Review 5.  Educational interventions to improve prescription and dispensing of antibiotics: a systematic review.

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6.  A retrospective audit of antibiotic prescriptions in primary health-care facilities in Eastern Region, Ghana.

Authors:  Mary-Anne Ahiabu; Britt P Tersbøl; Richard Biritwum; Ib C Bygbjerg; Pascal Magnussen
Journal:  Health Policy Plan       Date:  2015-06-04       Impact factor: 3.344

7.  Reduction of antibiotic prescriptions for acute respiratory tract infections in primary care: a systematic review.

Authors:  Anna Köchling; Christin Löffler; Stefan Reinsch; Anne Hornung; Femke Böhmer; Attila Altiner; Jean-François Chenot
Journal:  Implement Sci       Date:  2018-03-20       Impact factor: 7.327

Review 8.  Antibiotic resistance amongst healthcare-associated pathogens in China.

Authors:  Saber Yezli; Han Li
Journal:  Int J Antimicrob Agents       Date:  2012-09-20       Impact factor: 5.283

9.  Changes in antibiotic prescription following an education strategy for acute respiratory infections.

Authors:  Eloisa Delsors; Francisco Monsó; Francisco Javier López-Román; Juan Francisco Menárguez-Puche; María Gonzalez-Barberá; Hana Hukelova; Maria Teresa Martínez-Ros; Asensio López-Santiago
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10.  The comparative interrupted time series design for assessment of diagnostic impact: methodological considerations and an example using point-of-care C-reactive protein testing.

Authors:  Thomas R Fanshawe; Philip J Turner; Marjorie M Gillespie; Gail N Hayward
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  10 in total

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