Literature DB >> 16954196

A malleable catalyst dominates the metabolism of drugs.

F Peter Guengerich1.   

Abstract

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Year:  2006        PMID： 16954196      PMCID： PMC1564253          DOI： 10.1073/pnas.0606333103

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


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  19 in total

Review 1.  Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions.

Authors:  W Tang; R A Stearns
Journal:  Curr Drug Metab       Date:  2001-06       Impact factor: 3.731

2.  Comparison of experimental binding data and theoretical models in proteins containing subunits.

Authors:  D E Koshland; G Némethy; D Filmer
Journal:  Biochemistry       Date:  1966-01       Impact factor: 3.162

3.  Structural basis for ligand promiscuity in cytochrome P450 3A4.

Authors:  Marika Ekroos; Tove Sjögren
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-05       Impact factor: 11.205

4.  Substrate-induced conformational changes in the transmembrane segments of human P-glycoprotein. Direct evidence for the substrate-induced fit mechanism for drug binding.

Authors:  Tip W Loo; M Claire Bartlett; David M Clarke
Journal:  J Biol Chem       Date:  2003-02-27       Impact factor: 5.157

5.  Identification of an inducible form of cytochrome P-450 in human liver.

Authors:  P B Watkins; S A Wrighton; P Maurel; E G Schuetz; G Mendez-Picon; G A Parker; P S Guzelian
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

6.  Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone.

Authors:  Pamela A Williams; Jose Cosme; Dijana Matak Vinkovic; Alison Ward; Hayley C Angove; Philip J Day; Clemens Vonrhein; Ian J Tickle; Harren Jhoti
Journal:  Science       Date:  2004-07-15       Impact factor: 47.728

7.  Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

Authors:  F P Guengerich; M V Martin; P H Beaune; P Kremers; T Wolff; D J Waxman
Journal:  J Biol Chem       Date:  1986-04-15       Impact factor: 5.157

8.  Pyrene.pyrene complexes at the active site of cytochrome P450 3A4: evidence for a multiple substrate binding site.

Authors:  Michael J Dabrowski; Michael L Schrag; Larry C Wienkers; William M Atkins
Journal:  J Am Chem Soc       Date:  2002-10-09       Impact factor: 15.419

Review 9.  Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios.

Authors:  J Andrew Williams; Ruth Hyland; Barry C Jones; Dennis A Smith; Susan Hurst; Theunis C Goosen; Vincent Peterkin; Jeffrey R Koup; Simon E Ball
Journal:  Drug Metab Dispos       Date:  2004-08-10       Impact factor: 3.922

10.  The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution.

Authors:  Jason K Yano; Michael R Wester; Guillaume A Schoch; Keith J Griffin; C David Stout; Eric F Johnson
Journal:  J Biol Chem       Date:  2004-07-16       Impact factor: 5.157
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  14 in total

Review 1.  Substrate binding to cytochromes P450.

Authors:  Emre M Isin; F Peter Guengerich
Journal:  Anal Bioanal Chem       Date:  2008-07-13       Impact factor: 4.142

2.  Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450.

Authors:  Piotr J Mak; Ilia G Denisov; Yelena V Grinkova; Stephen G Sligar; James R Kincaid
Journal:  J Am Chem Soc       Date:  2011-01-05       Impact factor: 15.419

3.  7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites.

Authors:  Glenn A Marsch; Benjamin T Carlson; F Peter Guengerich
Journal:  J Biomol Struct Dyn       Date:  2017-03-20

4.  Characterization of Interactions Among CYP1A2, CYP2B4, and NADPH-cytochrome P450 Reductase: Identification of Specific Protein Complexes.

Authors:  J Patrick Connick; James R Reed; Wayne L Backes
Journal:  Drug Metab Dispos       Date:  2017-12-12       Impact factor: 3.922

5.  Structural insights on bioremediation of polycyclic aromatic hydrocarbons using microalgae: a modelling-based computational study.

Authors:  Pandian SureshKumar; Jibu Thomas; Vasudevan Poornima
Journal:  Environ Monit Assess       Date:  2018-01-22       Impact factor: 2.513

6.  Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.

Authors:  Aleksandra Z Kijac; Ying Li; Stephen G Sligar; Chad M Rienstra
Journal:  Biochemistry       Date:  2007-11-07       Impact factor: 3.162

7.  Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.

Authors:  Dorota Tomalik-Scharte; Dominique Maiter; Julia Kirchheiner; Hannah E Ivison; Uwe Fuhr; Wiebke Arlt
Journal:  Eur J Endocrinol       Date:  2010-09-15       Impact factor: 6.664

Review 8.  The functional effects of physical interactions involving cytochromes P450: putative mechanisms of action and the extent of these effects in biological membranes.

Authors:  James R Reed; Wayne L Backes
Journal:  Drug Metab Rev       Date:  2016-08       Impact factor: 4.518

9.  QM/MM Simulation on P450 BM3 Enzyme Catalysis Mechanism.

Authors:  Li Tian; Richard A Friesner
Journal:  J Chem Theory Comput       Date:  2009       Impact factor: 6.006

10.  Rationalization of stereospecific binding of propranolol to cytochrome P450 2D6 by free energy calculations.

Authors:  Gabor Nagy; Chris Oostenbrink
Journal:  Eur Biophys J       Date:  2012-10-20       Impact factor: 1.733
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