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Literature DB >> 16950653

Fatty acid synthesis and elongation in yeast.

Oksana Tehlivets¹, Kim Scheuringer, Sepp D Kohlwein.

Abstract

Fatty acids are essential compounds in the cell. Since the yeast Saccharomyces cerevisiae does not feed typically on fatty acids, cellular function and growth relies on endogenous synthesis. Since all cellular organelles are involved in--or dependent on--fatty acid synthesis, multiple levels of control may exist to ensure proper fatty acid composition and homeostasis. In this review, we summarize what is currently known about enzymes involved in cellular fatty acid synthesis and elongation, and discuss potential links between fatty acid metabolism, physiology and cellular regulation.

Entities: Chemical Species

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Year: 2006 PMID： 16950653 DOI： 10.1016/j.bbalip.2006.07.004

Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002

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Cited

137 in total

1. Species disparity response to mutagenesis of marine yeasts for the potential production of biodiesel.

Authors: Thomas Breuck; Boutheina Bessadok; Andrea Santulli; Thomas Brück; Saloua Sadok
Journal: Biotechnol Biofuels Date: 2019-05-22 Impact factor: 6.040

2. The stearoyl-coenzyme A desaturase 1 is essential for virulence and membrane stress in Candida parapsilosis through unsaturated fatty acid production.

Authors: Long Nam Nguyen; Attila Gacser; Joshua D Nosanchuk
Journal: Infect Immun Date: 2010-10-25 Impact factor: 3.441

3. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect".

Authors: Jason M Crawford; Anna L Vagstad; Karen P Whitworth; Kenneth C Ehrlich; Craig A Townsend
Journal: Chembiochem Date: 2008-05-05 Impact factor: 3.164

10. Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.

Authors: Kentaro Kajiwara; Reika Watanabe; Harald Pichler; Kensuke Ihara; Suguru Murakami; Howard Riezman; Kouichi Funato
Journal: Mol Biol Cell Date: 2008-02-20 Impact factor: 4.138

Fatty acid synthesis and elongation in yeast.

1. Species disparity response to mutagenesis of marine yeasts for the potential production of biodiesel.

2. The stearoyl-coenzyme A desaturase 1 is essential for virulence and membrane stress in Candida parapsilosis through unsaturated fatty acid production.

3. Synthetic strategy of nonreducing iterative polyketide synthases and the origin of the classical "starter-unit effect".

Review 4. SLipid-induced cell dysfunction and cell death: lessons from yeast.

5. Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.

6. Two histone deacetylases, FfHda1 and FfHda2, are important for Fusarium fujikuroi secondary metabolism and virulence.

7. Generation and characterisation of stable ethanol-tolerant mutants of Saccharomyces cerevisiae.

Review 8. Biosynthesis and function of polyacetylenes and allied natural products.

9. Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast.

10. Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.