PURPOSE: The aim of this study was to investigate the frequency and characteristics of a docetaxel-induced radiation recall phenomenon. METHODS AND MATERIALS: Past histories of radiotherapy and radiation recall phenomenon (RRP) were analyzed in 461 patients who were administered docetaxel at our hospital between September 2002 and November 2005. RESULTS: Of the 461 patients, 171 underwent radiotherapy before starting docetaxel. RRP was noted in 3 patients (1.8%). The 3 cases show that RRP tends to develop in patients treated with lower-energy photon beams of < or =6 MV and in patients with marked acute phase reactions during radiotherapy. CONCLUSIONS: The incidence of RRP induced by docetaxel was 1.8%, making it a comparatively rare condition. However, docetaxel is increasingly being used for patients with head and neck tumors, and caution regarding development of RRP is warranted after use of docetaxel after high-dose radiotherapy with photon beams of < or =6 MV.
PURPOSE: The aim of this study was to investigate the frequency and characteristics of a docetaxel-induced radiation recall phenomenon. METHODS AND MATERIALS: Past histories of radiotherapy and radiation recall phenomenon (RRP) were analyzed in 461 patients who were administered docetaxel at our hospital between September 2002 and November 2005. RESULTS: Of the 461 patients, 171 underwent radiotherapy before starting docetaxel. RRP was noted in 3 patients (1.8%). The 3 cases show that RRP tends to develop in patients treated with lower-energy photon beams of < or =6 MV and in patients with marked acute phase reactions during radiotherapy. CONCLUSIONS: The incidence of RRP induced by docetaxel was 1.8%, making it a comparatively rare condition. However, docetaxel is increasingly being used for patients with head and neck tumors, and caution regarding development of RRP is warranted after use of docetaxel after high-dose radiotherapy with photon beams of < or =6 MV.
Authors: Sagar C Patel; Arnold C Paulino; Danielle Johnston; Lee Wiederhold; Richard Castillo; Rajkumar Venkatramani Journal: Pract Radiat Oncol Date: 2016-06-15
Authors: Vincent Sibaud; Nicole R Lebœuf; Henri Roche; Viswanath R Belum; Laurence Gladieff; Marion Deslandres; Marion Montastruc; Audrey Eche; Emmanuelle Vigarios; Florence Dalenc; Mario E Lacouture Journal: Eur J Dermatol Date: 2016-10-01 Impact factor: 3.328
Authors: Vinita Takiar; Eric A Strom; Donald P Baumann; Funda Meric-Bernstam; Ricardo H Alvarez; Ana M Gonzalez-Angulo Journal: Oncologist Date: 2013-02-12