Docetaxel induces radiation recall myositis: A case report.

The present study described a radiation recall (RR) myositis case following docetaxel chemotherapy in a 26-year-old female with metastatic breast cancer. The left pubis and left femur head and neck were treated with palliative radiotherapy to a dose of 20 Gy in 5 daily fractions. After 2 months, a whole-body positron emission tomography scan revealed new lesions, and systemic treatment was initiated with docetaxel chemotherapy (75 mg/m2, every 3 weeks). After the second dose, the patient started to feel pain in her left femur with erythema on her skin on the lumbar and gluteal region, in addition to swelling. On magnetic resonance imaging, edematous changes, increased signal enhancement on T2 and increased contrast uptake of muscles were observed, suggesting myositis on the irradiated field. The present study is the second case report published on the literature on RR myositis following docetaxel treatment, which emphasizes the importance of awareness about this phenomenon when considering differential diagnosis of pain.