Literature DB >> 16948885

Treatment of esophageal achalasia with Heller myotomy: retrospective evaluation of patient satisfaction and disease-specific quality of life.

Yen Dang1, Dale Mercer.   

Abstract

BACKGROUND: Prospective randomized studies have suggested that surgery palliates esophageal achalasia more effectively than pneumatic dilatation, but for some dilatation is still the procedure of choice for initial treatment. We decided to compare achalasia symptoms before and after Heller myotomy by means of postoperative questionnaires.
METHODS: The study included 22 patients who underwent Heller myotomy for achalasia at the Hotel Dieu Hospital, Queen's University, Kingston, Ont., since July 1990; 5 of them required repeat myotomy for symptom recurrence, for a total of 9 open and 18 laparoscopic procedures. Median follow-up was 43 (range 6-109) months. Preoperative and postoperative data regarding dysphagia, regurgitation, chest pain and overall patient satisfaction were gathered. Symptom scores were calculated by adding severity (0 = none, 2 = mild, 4 = moderate, 6 = severe) to frequency (0 = never, 1 = occasionally, 2 = once a month, 3 = every week, 4 = twice a week, 5 = daily). Patients having a repeat procedure were instructed to evaluate symptoms with respect to their initial myotomy.
RESULTS: Seventeen (77%) patients were successfully contacted, 4 of them had subsequent repeat myotomy for symptom recurrence. Initially, overall symptom scores decreased for all but 1 patient, with mean preoperative and postoperative values of 23.1 and 7.3 respectively (p < 0.001). The patient in whom symptoms did not improve is a candidate for a repeat procedure. Repeat myotomy was performed after a median of 38 (range 23-75) months, corresponding to an overall 3-year positive outcome in 13 (76%) of the 17 patients. Fifteen (88%) patients considered their myotomies a success and 16 (94%) would choose to have this procedure again given the outcome.
CONCLUSION: Heller myotomy appears to be effective in alleviating the symptoms of achalasia. Repeat myotomy is occasionally required.

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Mesh:

Year:  2006        PMID: 16948885      PMCID: PMC3207570     

Source DB:  PubMed          Journal:  Can J Surg        ISSN: 0008-428X            Impact factor:   2.089


  23 in total

Review 1.  Comparison and cost analysis of different treatment strategies in achalasia.

Authors:  J E Richter
Journal:  Gastrointest Endosc Clin N Am       Date:  2001-04

Review 2.  Laparoscopic myotomy: technique and efficacy in treating achalasia.

Authors:  A Ali; C A Pellegrini
Journal:  Gastrointest Endosc Clin N Am       Date:  2001-04

3.  Etiology, diagnosis, and treatment of failures after laparoscopic Heller myotomy for achalasia.

Authors:  Giovanni Zaninotto; Mario Costantini; Giuseppe Portale; Giorgio Battaglia; Daniela Molena; Alessanda Carta; Michela Costantino; Loredana Nicoletti; Ermanno Ancona
Journal:  Ann Surg       Date:  2002-02       Impact factor: 12.969

Review 4.  Achalasia: a review of therapeutic options and outcomes.

Authors:  Eduardo B V Da Silveira; Arvey I Rogers
Journal:  Compr Ther       Date:  2002

5.  Isosorbide dinitrate and nifedipine treatment of achalasia: a clinical, manometric and radionuclide evaluation.

Authors:  M Gelfond; P Rozen; T Gilat
Journal:  Gastroenterology       Date:  1982-11       Impact factor: 22.682

6.  Impact of minimally invasive surgery on the treatment of esophageal achalasia: a decade of change.

Authors:  Marco G Patti; Piero M Fisichella; Silvana Perretta; Carlos Galvani; Maria V Gorodner; Thomas Robinson; Lawrence W Way
Journal:  J Am Coll Surg       Date:  2003-05       Impact factor: 6.113

7.  Epidemiology of hospitalization for achalasia in the United States.

Authors:  A Sonnenberg; B T Massey; D J McCarty; S J Jacobsen
Journal:  Dig Dis Sci       Date:  1993-02       Impact factor: 3.199

8.  A prospective randomized study comparing forceful dilatation and esophagomyotomy in patients with achalasia of the esophagus.

Authors:  A Csendes; N Velasco; I Braghetto; A Henriquez
Journal:  Gastroenterology       Date:  1981-04       Impact factor: 22.682

9.  Effect of nitrates on LOS pressure in achalasia: a potential therapeutic aid.

Authors:  M Gelfond; P Rozen; S Keren; T Gilat
Journal:  Gut       Date:  1981-04       Impact factor: 23.059

10.  Late results of a prospective randomised study comparing forceful dilatation and oesophagomyotomy in patients with achalasia.

Authors:  A Csendes; I Braghetto; A Henríquez; C Cortés
Journal:  Gut       Date:  1989-03       Impact factor: 23.059

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  9 in total

1.  Surgical options for treatment of esophageal motility disorders.

Authors:  Brant K Oelschlager
Journal:  Gastroenterol Hepatol (N Y)       Date:  2007-09

2.  Effect of laparoscopic esophagomyotomy on chest pain associated with achalasia and prediction of therapeutic outcomes.

Authors:  Nobuo Omura; Hideyuki Kashiwagi; Fumiaki Yano; Kazuto Tsuboi; Yoshio Ishibashi; Masato Hoshino; Katsuhiko Yanaga
Journal:  Surg Endosc       Date:  2010-09-11       Impact factor: 4.584

3.  Surgical treatment for nonspecific esophageal motility disorders.

Authors:  Takanori Inose; Tatsuya Miyazaki; Shigemasa Suzuki; Naritaka Tanaka; Makoto Sakai; Akihiko Sano; Takehiko Yokobori; Makoto Sohda; Masanobu Nakajima; Minoru Fukuchi; Hiroyuki Kato; Hiroyuki Kuwano
Journal:  Surg Today       Date:  2012-12-18       Impact factor: 2.549

4.  Pneumatic balloon dilation therapy is as effective as esophagomyotomy for achalasia.

Authors:  Mohammad Hassan Emami; Mostafa Raisi; Jaleh Amini; Abbas Tabatabai; Mehran Haghighi; Hamid Tavakoli; Mozafar Hashemi; Mehdi Fude; Ziba Farajzadegan; Vahid Goharian
Journal:  Dysphagia       Date:  2008-02-06       Impact factor: 3.438

5.  Results of the surgical treatment of non-advanced megaesophagus using Heller-Pinotti's surgery: Laparotomy vs. Laparoscopy.

Authors:  Luiz Roberto Lopes; Nathália da Silva Braga; Gustavo Carvalho de Oliveira; João de Souza Coelho Neto; Marcelo Amade Camargo; Nelson Adami Andreollo
Journal:  Clinics (Sao Paulo)       Date:  2011       Impact factor: 2.365

Review 6.  Idiopathic (primary) achalasia: a review.

Authors:  Dhyanesh A Patel; Hannah P Kim; Jerry S Zifodya; Michael F Vaezi
Journal:  Orphanet J Rare Dis       Date:  2015-07-22       Impact factor: 4.123

Review 7.  Idiopathic (primary) achalasia.

Authors:  Farnoosh Farrokhi; Michael F Vaezi
Journal:  Orphanet J Rare Dis       Date:  2007-09-26       Impact factor: 4.123

8.  The early efficacy of Heller myotomy in the treatment of Iranian patients with achalasia.

Authors:  Saeed Abdi; Mojgan Forotan; Abdolrahim Nikzamir; Saeedeh Zomorody; Somayeh Jahani-Sherafat
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2016

9.  LATE EVALUATION OF DYSPHAGIA AFTER HELLER ESOPHAGEAL MYOTOMY WITH DOR FUNDOPLICATION FOR ACHALASIA.

Authors:  Eduardo Rodrigues Zarco Câmara; Fernando Athayde Veloso Madureira; Delta Madureira; Renato Manganelli Salomão; Antonio Carlos Ribeiro Garrido Iglesias
Journal:  Arq Bras Cir Dig       Date:  2017 Jul-Sep
  9 in total

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