Literature DB >> 16944176

Successful developmental outcome in intrauterine myelomeningocele repair.

Helder Zambelli1, Ricardo Barini, Alexandre Iscaife, Kleber Cursino, Angélica de Fátima A Braga, Sérgio Marba, Lourenço Sbragia.   

Abstract

INTRODUCTION: Myelomeningocele (MM) is one of the forms of dysraphism. Hydrocephalus secondary to Arnold-Chiari (AC) malformation is responsible for the morbidity and mortality of the disease. The intrauterine repair of MM may reverse AC and limit hydrocephalus progression.
OBJECTIVE: The aim of this work is to report the successful outcome of a case of intrauterine correction of MM, with favorable evolution and birth at 36 weeks of pregnancy. CASE REPORT: KCMC, 19 years old, was submitted to intrauterine repair of MM at 24 weeks of gestational age after approval by the family and the Research Ethics Committee of the School of Medical Sciences-UNICAMP.
CONCLUSION: Although it is not the standard option for surgical correction, selected MM cases with early fetal diagnosis may be eligible for intrauterine repair, when there is consensus with the Research Ethics Committees and family members.

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Year:  2006        PMID: 16944176     DOI: 10.1007/s00381-006-0169-5

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  14 in total

Review 1.  The Rationale for in utero repair of myelomeningocele.

Authors:  D S Walsh; N S Adzick; L N Sutton; M P Johnson
Journal:  Fetal Diagn Ther       Date:  2001 Sep-Oct       Impact factor: 2.587

2.  Endoscopic coverage of fetal open myelomeningocele in utero.

Authors:  J P Bruner; N E Tulipan; W O Richards
Journal:  Am J Obstet Gynecol       Date:  1997-01       Impact factor: 8.661

3.  Economic burden of spina bifida--United States, 1980-1990.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  1989-04-21       Impact factor: 17.586

4.  Fetal surgery for myelomeningocele and the incidence of shunt-dependent hydrocephalus.

Authors:  J P Bruner; N Tulipan; R L Paschall; F H Boehm; W F Walsh; S R Silva; M Hernanz-Schulman; L H Lowe; G W Reed
Journal:  JAMA       Date:  1999-11-17       Impact factor: 56.272

5.  In utero surgery rescues neurological function at birth in sheep with spina bifida.

Authors:  M Meuli; C Meuli-Simmen; G M Hutchins; C D Yingling; K M Hoffman; M R Harrison; N S Adzick
Journal:  Nat Med       Date:  1995-04       Impact factor: 53.440

6.  Longevity of patients born with myelomeningocele.

Authors:  C M Dillon; B E Davis; S Duguay; K D Seidel; D B Shurtleff
Journal:  Eur J Pediatr Surg       Date:  2000-12       Impact factor: 2.191

7.  Hindbrain herniation develops in surgically created myelomeningocele but is absent after repair in fetal lambs.

Authors:  B W Paek; D L Farmer; C C Wilkinson; C T Albanese; W Peacock; M R Harrison; R W Jennings
Journal:  Am J Obstet Gynecol       Date:  2000-11       Impact factor: 8.661

8.  A new look at myelomeningoceles: functional level, vertebral level, shunting, and the implications for fetal intervention.

Authors:  Natalie E Rintoul; Leslie N Sutton; Anne M Hubbard; Brian Cohen; Jeanne Melchionni; Patrick S Pasquariello; N Scott Adzick
Journal:  Pediatrics       Date:  2002-03       Impact factor: 7.124

9.  Intrauterine treatment of spina bifida: primate model.

Authors:  M Michejda
Journal:  Z Kinderchir       Date:  1984-08

10.  Prevalence of spina bifida at birth--United States, 1983-1990: a comparison of two surveillance systems.

Authors:  J M Lary; L D Edmonds
Journal:  MMWR CDC Surveill Summ       Date:  1996-04-19
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  3 in total

1.  Therapeutic potential of in utero mesenchymal stem cell (MSCs) transplantation in rat foetuses with spina bifida aperta.

Authors:  Hui Li; Fei Gao; Lili Ma; Junhong Jiang; Jianing Miao; Mingyu Jiang; Yang Fan; Lili Wang; Di Wu; Bo Liu; Weilin Wang; Vincent Chi Hang Lui; Zhengwei Yuan
Journal:  J Cell Mol Med       Date:  2012-07       Impact factor: 5.310

2.  Application potential of bone marrow mesenchymal stem cell (BMSCs) based tissue-engineering for spinal cord defect repair in rat fetuses with spina bifida aperta.

Authors:  Xiaoshuai Li; Zhengwei Yuan; Xiaowei Wei; Hui Li; Guifeng Zhao; Jiaoning Miao; Di Wu; Bo Liu; Songying Cao; Dong An; Wei Ma; Henan Zhang; Weilin Wang; Qiushi Wang; Hui Gu
Journal:  J Mater Sci Mater Med       Date:  2016-02-19       Impact factor: 3.896

Review 3.  Anesthesia for fetal operative procedures: A systematic review.

Authors:  Miriam Duci; Rebecca Pulvirenti; Francesco Fascetti Leon; Irma Capolupo; Paola Veronese; Piergiorgio Gamba; Costanza Tognon
Journal:  Front Pain Res (Lausanne)       Date:  2022-09-12
  3 in total

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