Literature DB >> 16943522

What is the right dose? The elusive optimal biologic dose in phase I clinical trials.

Alex A Adjei.   

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Year:  2006        PMID: 16943522     DOI: 10.1200/JCO.2006.07.4658

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


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  28 in total

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Review 2.  Envisioning the future of early anticancer drug development.

Authors:  Timothy A Yap; Shahneen K Sandhu; Paul Workman; Johann S de Bono
Journal:  Nat Rev Cancer       Date:  2010-06-10       Impact factor: 60.716

Review 3.  Translational research in phase I trials.

Authors:  Angelica Fasolo; Cristiana Sessa
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Review 4.  A pharmacologic perspective on newly emerging T-cell manipulation technologies.

Authors:  Dominic Smethurst
Journal:  Br J Clin Pharmacol       Date:  2013-08       Impact factor: 4.335

Review 5.  Determining the optimal dose in the development of anticancer agents.

Authors:  Ron H J Mathijssen; Alex Sparreboom; Jaap Verweij
Journal:  Nat Rev Clin Oncol       Date:  2014-03-25       Impact factor: 66.675

6.  Exposure-response relationship of AMG 386 in combination with weekly paclitaxel in recurrent ovarian cancer and its implication for dose selection.

Authors:  Jian-Feng Lu; Erik Rasmussen; Beth Y Karlan; Ignace B Vergote; Lynn Navale; Mita Kuchimanchi; Rebeca Melara; Daniel E Stepan; David M Weinreich; Yu-Nien Sun
Journal:  Cancer Chemother Pharmacol       Date:  2012-01-01       Impact factor: 3.333

Review 7.  PROteolysis TArgeting Chimeras (PROTACs) - Past, present and future.

Authors:  Mariell Pettersson; Craig M Crews
Journal:  Drug Discov Today Technol       Date:  2019-02-13

Review 8.  Induced protein degradation: an emerging drug discovery paradigm.

Authors:  Ashton C Lai; Craig M Crews
Journal:  Nat Rev Drug Discov       Date:  2016-11-25       Impact factor: 84.694

Review 9.  The inverted pyramid of biomarker-driven trials.

Authors:  Ignacio Garrido-Laguna; Manuel Hidalgo; Razelle Kurzrock
Journal:  Nat Rev Clin Oncol       Date:  2011-08-02       Impact factor: 66.675

10.  Phase I study of azacitidine following donor lymphocyte infusion for relapsed acute myeloid leukemia post allogeneic stem cell transplantation.

Authors:  Armin Ghobadi; Jaebok Choi; Mark A Fiala; Theresa Fletcher; Jingxia Liu; Linda G Eissenberg; Camille Abboud; Amanda Cashen; Ravi Vij; Mark A Schroeder; Iskra Pusic; Keith Stockerl-Goldstein; Meagan Jacoby; Geoffrey Uy; John DiPersio; Peter Westervelt
Journal:  Leuk Res       Date:  2016-07-22       Impact factor: 3.156

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