BACKGROUND: Some blood donation-related adverse events (AEs) can negatively impact the blood donor return rate (BDRR) and decrease donor retention. STUDY DESIGN AND METHODS: One-thousand randomly selected whole-blood donors were interviewed 3 weeks after a 525-mL index whole-blood donation for seven AEs. The number of return visits and duration of follow-up were recorded for each of the 1000 donors. A negative binomial regression analysis was used to determine the contribution of the four most common AEs to the BDRR, and interactions between these AEs were also evaluated. RESULTS: The four most common AEs were bruise alone (15.1%), sore arm "alone" (7.0%), fatigue "alone" (5.1%), and donor reaction "alone" (4.2%), where "alone" is defined to also include donors who had a bruise but no other AE. The estimated BDRR for donations without AEs was 1.32 visits per year. The estimated BDRRs for the four most common AEs were: bruise alone, 1.32 visits per year; sore arm alone, 1.30 visits per year (2% reduction in BDRR); fatigue alone, 1.06 visits per year (20% reduction in BDRR); and donor reaction alone, 0.87 visits per year (34% reduction in BDRR). The BDRR for donor reaction, fatigue, and sore arm together was 0.20 visits per year (85% reduction in BDRR). CONCLUSION: Donor reaction had the most negative impact on the BDRR. There appears to be a synergistic effect between donor reaction, fatigue, and sore arm. Theoretically, amelioration of some AEs has the potential to improve BDRRs.
RCT Entities:
BACKGROUND: Some blood donation-related adverse events (AEs) can negatively impact the blood donor return rate (BDRR) and decrease donor retention. STUDY DESIGN AND METHODS: One-thousand randomly selected whole-blood donors were interviewed 3 weeks after a 525-mL index whole-blood donation for seven AEs. The number of return visits and duration of follow-up were recorded for each of the 1000 donors. A negative binomial regression analysis was used to determine the contribution of the four most common AEs to the BDRR, and interactions between these AEs were also evaluated. RESULTS: The four most common AEs were bruise alone (15.1%), sore arm "alone" (7.0%), fatigue "alone" (5.1%), and donor reaction "alone" (4.2%), where "alone" is defined to also include donors who had a bruise but no other AE. The estimated BDRR for donations without AEs was 1.32 visits per year. The estimated BDRRs for the four most common AEs were: bruise alone, 1.32 visits per year; sore arm alone, 1.30 visits per year (2% reduction in BDRR); fatigue alone, 1.06 visits per year (20% reduction in BDRR); and donor reaction alone, 0.87 visits per year (34% reduction in BDRR). The BDRR for donor reaction, fatigue, and sore arm together was 0.20 visits per year (85% reduction in BDRR). CONCLUSION:Donor reaction had the most negative impact on the BDRR. There appears to be a synergistic effect between donor reaction, fatigue, and sore arm. Theoretically, amelioration of some AEs has the potential to improve BDRRs.
Authors: Thelma T Gonçalez; Ester C Sabino; Karen S Schlumpf; David J Wright; Silvana Leao; Divaldo Sampaio; Pedro L Takecian; Anna B Proietti; Anna B Proitetti; Edward Murphy; Michael Busch; Brian Custer Journal: Transfusion Date: 2011-11-11 Impact factor: 3.157
Authors: Johanna C Wiersum-Osselton; Tanneke Marijt-van der Kreek; Anneke Brand; Ingrid Veldhuizen; Johanna G van der Bom; Wim de Kort Journal: Blood Transfus Date: 2013-06-03 Impact factor: 3.443
Authors: Christian Weidmann; Michael Müller-Steinhardt; Sven Schneider; Eberhard Weck; Harald Klüter Journal: Transfus Med Hemother Date: 2011-12-23 Impact factor: 3.747
Authors: Maurits D Hoogerwerf; Ingrid J T Veldhuizen; Wim L A M De Kort; Monique H W Frings-Dresen; Judith K Sluiter Journal: Blood Transfus Date: 2015-01-29 Impact factor: 3.443
Authors: Anne Wevers; Daniël H J Wigboldus; Wim L A M de Kort; Rick van Baaren; Ingrid J T Veldhuizen Journal: Blood Transfus Date: 2013-03-01 Impact factor: 3.443