| Literature DB >> 16930645 |
Liam Evans1, John N Hedger, David Brayford, Michael Stavri, Eileen Smith, Gemma O'Donnell, Alexander I Gray, Gareth W Griffith, Simon Gibbons.
Abstract
A fusidane triterpene, 16-deacetoxy-7-beta-hydroxy-fusidic acid (1), was isolated from a fermentation of the mitosporic fungus Acremonium crotocinigenum. Full unambiguous assignment of all (1)H and (13)C data of 1 was carried out by extensive one- and two-dimensional NMR studies employing HMQC and HMBC spectra. Compound 1 was tested against a panel of multidrug-resistant (MDR) and methicillin-resistant Staphylococcus aureus (MRSA) strains and showed minimum inhibitory concentration values of 16 microg/ml.Entities:
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Year: 2006 PMID： 16930645 DOI： 10.1016/j.phytochem.2006.06.033
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072