Literature DB >> 16927539

Synthesis of certain new thiieno [2,3-d] pyrimidines as potential antitumor and radioprotective agents.

Mostafa M Ghorab1, Fatma A Ragab, Eman Noaman, Helmy I Heiba, Marwa Galal.   

Abstract

During research on anticancer and radioprotective heterocyclic compounds containing thiophene ring 5-10, 15, 19, thieno[2,3-d]pyrimidines 11-14 and biscompound having thieno[2,3-d]pyrimidine 18 were synthesized. The synthesized compounds were characterized by elemental ananlysis, IR, 1H-NMR and mass spectral data. Some of the obtained compounds showed interesting antitumor and radioprotective activities.

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Year:  2006        PMID: 16927539     DOI: 10.1055/s-0031-1296751

Source DB:  PubMed          Journal:  Arzneimittelforschung        ISSN: 0004-4172


  1 in total

1.  (E)-3-Dimethyl-amino-1-(2,5-dimethyl-thio-phen-3-yl)prop-2-en-1-one.

Authors:  Mostafa M Ghorab; Mansour S Al-Said; Hazem A Ghabbour; Tze Shyang Chia; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-05-12
  1 in total

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