Literature DB >> 16921690

Modification of a biventricular assist device to facilitate preservative infusion and organ recovery in a nonheart-beating donor.

Ron Angona1, Peter Abt, Duraid Younan, Todd Massey, Michael Marvin, Randeep Kashyap, Dan Richards, Karen Jones, James Queschenbach, Martin Zand, Ashok Jain, Mark Orloff, Adel Bozorgzadeh.   

Abstract

A 46-year-old patient supported by a biventricular assist device (BiVAD) was transferred to our institution for evaluation for heart transplant. The patient was found to have a large intracranial hemorrhage with profound deterioration of neurologic status. The poor prognosis prompted the decision to withdraw care and pursue organ donation. Because the patient did not meet brain death criteria, nonheart-beating donor organ donation was pursued. After the termination of care, the BiVAD was modified: the left side to provide organ preservative solution and the right side to allow drainage. Eight liters of cold University of Wisconsin solution were pumped systemically over 10 minutes, the donor was drained, and the liver was harvested. This technique expedited donor perfusion by eliminating the need to cannulate, minimizing ischemic time for the liver. Although the recipient outcome was poor, and retransplantation was eventually necessary, we believe it was most likely not attributable to the quality of organ preservation. This report discusses the technical aspects of this potentially beneficial procedure.

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Mesh:

Year:  2006        PMID: 16921690      PMCID: PMC4680753     

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  10 in total

1.  Kidney transplantation from donors without a heartbeat.

Authors:  Markus Weber; Daniel Dindo; Nicholas Demartines; Patrice M Ambühl; Pierre-Alain Clavien
Journal:  N Engl J Med       Date:  2002-07-25       Impact factor: 91.245

2.  Simultaneous pancreas-kidney (SPK) transplantation from controlled non-heart-beating donors (NHBDs).

Authors:  A M D'Alessandro; J S Odorico; S J Knechtle; Y T Becker; R M Hoffmann; M Kalayoglu; H W Sollinger
Journal:  Cell Transplant       Date:  2000 Nov-Dec       Impact factor: 4.064

3.  The effect of inadequate in situ perfusion in the non heart-beating donor.

Authors:  Muhammed A Gok; Aftab A Bhatti; John Asher; Ajay Gupta; Brian K Shenton; Helen Robertson; Naeem A Soomro; David Talbot
Journal:  Transpl Int       Date:  2005-10       Impact factor: 3.782

4.  Liver transplantation from controlled non-heart-beating donors.

Authors:  A M D'alessandro; R M Hoffmann; S J Knechtle; J S Odorico; Y T Becker; A Musat; J D Pirsch; H W Sollinger; M Kalayoglu
Journal:  Surgery       Date:  2000-10       Impact factor: 3.982

5.  Survival following liver transplantation from non-heart-beating donors.

Authors:  Peter L Abt; Niraj M Desai; Michael D Crawford; Lisa M Forman; Joseph W Markmann; Kim M Olthoff; James F Markmann
Journal:  Ann Surg       Date:  2004-01       Impact factor: 12.969

6.  Successful non-heart-beating donor organ retrieval in a patient with a left ventricular assist device.

Authors:  Stephen C Rayhill; Gustavo Martinez-Mier; Daniel A Katz; Subba Rao Kanchustambam; You Min Wu
Journal:  Am J Transplant       Date:  2004-01       Impact factor: 8.086

7.  Long-term outcome of controlled, non-heart-beating donor liver transplantation.

Authors:  Cosme Y Manzarbeitia; Jorge A Ortiz; Hoonbae Jeon; Kenneth D Rothstein; Oscar Martinez; Victor R Araya; Santiago J Munoz; David J Reich
Journal:  Transplantation       Date:  2004-07-27       Impact factor: 4.939

8.  Estimation and characterization of the potential renal organ donor pool in Pennsylvania. Report of the Pennsylvania Statewide Donor Study.

Authors:  H M Nathan; B E Jarrell; B Broznik; R Kochik; B Hamilton; S Stuart; T Ackroyd; M Nell
Journal:  Transplantation       Date:  1991-01       Impact factor: 4.939

9.  Experience with liver and kidney allografts from non-heart-beating donors.

Authors:  A Casavilla; C Ramirez; R Shapiro; D Nghiem; K Miracle; O Bronsther; P Randhawa; B Broznick; J J Fung; T Starzl
Journal:  Transplantation       Date:  1995-01-27       Impact factor: 4.939

10.  Neurological events during long-term mechanical circulatory support for heart failure: the Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) experience.

Authors:  Ronald M Lazar; Peter A Shapiro; Brian E Jaski; Michael K Parides; Robert C Bourge; John T Watson; Laura Damme; Walter Dembitsky; Jeffrey D Hosenpud; Lopa Gupta; Anita Tierney; Tonya Kraus; Yoshifumi Naka
Journal:  Circulation       Date:  2004-05-03       Impact factor: 29.690

  10 in total

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