Literature DB >> 16914761

Relapsing hypocupraemic myelopathy requiring high-dose oral copper replacement.

C I Prodan1, S S Bottomley, N R Holland, S E Lind.   

Abstract

Adult-onset copper deficiency with neurological manifestations is a newly recognised syndrome. Long-term oral copper replacement therapy has been the mainstay of treatment in the literature. A case of relapsing hypocupraemic myelopathy responsive to increased doses of copper replacement is reported. Standard doses of copper may not be sufficient for all patients.

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Year:  2006        PMID: 16914761      PMCID: PMC2077729          DOI: 10.1136/jnnp.2006.096883

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  14 in total

1.  CNS demyelination from zinc toxicity?

Authors:  C I Prodan; N R Holland
Journal:  Neurology       Date:  2000-04-25       Impact factor: 9.910

2.  Copper deficiency-associated myelopathy in a 46-year-old woman.

Authors:  B Schleper; H J Stuerenburg
Journal:  J Neurol       Date:  2001-08       Impact factor: 4.849

3.  CNS demyelination associated with copper deficiency and hyperzincemia.

Authors:  C I Prodan; N R Holland; P J Wisdom; S A Burstein; S S Bottomley
Journal:  Neurology       Date:  2002-11-12       Impact factor: 9.910

4.  A neurological and hematological syndrome associated with zinc excess and copper deficiency.

Authors:  Steven A Greenberg; Hannah R Briemberg
Journal:  J Neurol       Date:  2004-01       Impact factor: 4.849

5.  Neurologic aspects of cobalamin deficiency.

Authors:  E B Healton; D G Savage; J C Brust; T J Garrett; J Lindenbaum
Journal:  Medicine (Baltimore)       Date:  1991-07       Impact factor: 1.889

6.  Acquired hypocupremia after gastric surgery.

Authors:  Neeraj Kumar; J Eric Ahlskog; John B Gross
Journal:  Clin Gastroenterol Hepatol       Date:  2004-12       Impact factor: 11.382

7.  Myelopolyneuropathy and pancytopenia due to copper deficiency and high zinc levels of unknown origin: further support for existence of a new zinc overload syndrome.

Authors:  Peter Hedera; John K Fink; Paula L Bockenstedt; George J Brewer
Journal:  Arch Neurol       Date:  2003-09

Review 8.  Copper deficiency myelopathy produces a clinical picture like subacute combined degeneration.

Authors:  Neeraj Kumar; John B Gross; J Eric Ahlskog
Journal:  Neurology       Date:  2004-07-13       Impact factor: 9.910

9.  Copper deficiency masquerading as myelodysplastic syndrome.

Authors:  Xylina T Gregg; Vishnu Reddy; Josef T Prchal
Journal:  Blood       Date:  2002-08-15       Impact factor: 22.113

10.  Copper deficiency as cause of unexplained hematologic and neurologic deficits in patient with prior gastrointestinal surgery.

Authors:  Joanne Wu; Mari Ricker; John Muench
Journal:  J Am Board Fam Med       Date:  2006 Mar-Apr       Impact factor: 2.657

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  6 in total

1.  [Copper deficiency as a treatable cause of myelopathy].

Authors:  A Jung; M Marziniak
Journal:  Nervenarzt       Date:  2008-04       Impact factor: 1.214

Review 2.  Mineral malnutrition following bariatric surgery.

Authors:  Nana Gletsu-Miller; Breanne N Wright
Journal:  Adv Nutr       Date:  2013-09-01       Impact factor: 8.701

3.  When metals compete: a case of copper-deficiency myeloneuropathy and anemia.

Authors:  Rebecca I Spain; Thomas P Leist; Eduardo A De Sousa
Journal:  Nat Clin Pract Neurol       Date:  2009-02

Review 4.  Copper deficiency myelopathy.

Authors:  Stephan R Jaiser; Gavin P Winston
Journal:  J Neurol       Date:  2010-03-16       Impact factor: 4.849

5.  Impairment of interrelated iron- and copper homeostatic mechanisms in brain contributes to the pathogenesis of neurodegenerative disorders.

Authors:  Tina Skjørringe; Lisbeth Birk Møller; Torben Moos
Journal:  Front Pharmacol       Date:  2012-09-25       Impact factor: 5.810

6.  Copper deficiency caused by excessive alcohol consumption.

Authors:  Shunichi Shibazaki; Shuhei Uchiyama; Katsuji Tsuda; Norihide Taniuchi
Journal:  BMJ Case Rep       Date:  2017-09-26
  6 in total

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