Literature DB >> 16912816

Toxicology findings in child and adolescent suicides in virginia: 1987-2003.

W Victor R Vieweg1, Anand K Pandurangi, Emmanuel A Anum, Jack O Lanier, Marcella F Fierro, Antony Fernandez.   

Abstract

OBJECTIVE: In a follow-up report of child and adolescent suicides in Virginia, we describe postmortem toxicology findings in a subset of these youths.
METHOD: We analyzed "unnatural" deaths from Virginia's Office of the Chief Medical Examiner for 1987 to 2003. There were 2818 unnatural deaths in children and adolescents. We grouped unnatural deaths as accidents, homicides, and suicides. Toxicology records were available for 753 cases, of which 732 were black or white youths.
RESULTS: There were no age differences among suicide victims and accident or homicide victims. Whites were more likely than blacks to die by accident and suicide. White females were more likely than black females to commit suicide. Black males were more likely than white males to suffer homicide. For all unexpected deaths, antidepressants were more commonly found among whites than blacks. Suicide by poisoning occurred more commonly among whites. Recreational drugs were more commonly found among blacks than whites. Suicide by gun occurred more commonly among blacks. Antidepressants were found in 39 black and white suicide victims. Anti-depressants (all tricyclic antidepressants) were causally related in 17 cases of suicide by poisoning. No other antidepressants were found in lethal levels in suicide by poisoning. Selective serotonin reuptake inhibitors (SSRIs)/venlafaxine appeared more commonly in the suicides (p < .0001) than in accidents or homicides. For suicides, SSRIs appeared no more commonly in poisoning than in gun or hanging deaths (p = .695).
CONCLUSIONS: Antidepressants appeared more commonly among youths committing suicide than those dying by accident or homicide. SSRIs did not appear more commonly among youths committing suicide by poisoning than those committing suicide by gun or hanging. Because our data are descriptive, they are subject to over-interpretation. Cause-effect inferences should not be drawn.

Entities:  

Year:  2006        PMID: 16912816      PMCID: PMC1540399          DOI: 10.4088/pcc.v08n0303

Source DB:  PubMed          Journal:  Prim Care Companion J Clin Psychiatry        ISSN: 1523-5998


  5 in total

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Authors:  Thomas B Cole; Reneé M Johnson
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2.  Evaluating iatrogenic risk of youth suicide screening programs: a randomized controlled trial.

Authors:  Madelyn S Gould; Frank A Marrocco; Marjorie Kleinman; John Graham Thomas; Katherine Mostkoff; Jean Cote; Mark Davies
Journal:  JAMA       Date:  2005-04-06       Impact factor: 56.272

3.  Child and adolescent suicides in Virginia: 1987 to 2003.

Authors:  W Victor R Vieweg; Julie A Linker; Emmanuel A Anum; Elizabeth Turf; Anand K Pandurangi; Bela Sood; Marcella F Fierro; Antony Fernandez
Journal:  J Child Adolesc Psychopharmacol       Date:  2005-08       Impact factor: 2.576

4.  Gun storage practices and risk of youth suicide and unintentional firearm injuries.

Authors:  David C Grossman; Beth A Mueller; Christine Riedy; M Denise Dowd; Andres Villaveces; Janice Prodzinski; Jon Nakagawara; John Howard; Norman Thiersch; Richard Harruff
Journal:  JAMA       Date:  2005-02-09       Impact factor: 56.272

5.  Tricyclic antidepressants, QT interval prolongation, and torsade de pointes.

Authors:  W Victor R Vieweg; Mark A Wood
Journal:  Psychosomatics       Date:  2004 Sep-Oct       Impact factor: 2.386

  5 in total
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1.  Toxicological findings in suicides - frequency of antidepressant and antipsychotic substances.

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Review 2.  Proarrhythmic risk with antipsychotic and antidepressant drugs: implications in the elderly.

Authors:  W Victor R Vieweg; Mark A Wood; Antony Fernandez; Mary Beatty-Brooks; Mehrul Hasnain; Anand K Pandurangi
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

3.  Presence of Alcohol and Drugs in Hispanic Versus Non-Hispanic Youth Suicide Victims in Miami-Dade County, Florida.

Authors:  Daniel Castellanos; Jennifer Ellyn Kosoy; Karla Diaz Ayllon; Juan Acuna
Journal:  J Immigr Minor Health       Date:  2016-10

4.  Cases of adverse reaction to psychotropic drugs and possible association with pharmacogenetics.

Authors:  Irina Piatkov; Trudi Jones; Mark McLean
Journal:  J Pers Med       Date:  2012-10-01
  4 in total

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