Literature DB >> 16906194

Internal disc disruption and low back pain.

N Sehgal1, J D Fortin.   

Abstract

Internal disc disruption is a common cause of disabling low back pain in a substantial number of young, healthy adults. Crock described this painful entity and reported annular fissures that distort the internal architecture of the disc; Externally the disc appears relatively intact and undeformed. A clinical diagnosis of internal disc disruption, in absence of objective clinical findings, is extremely difficult. The only convincing means to establish the diagnosis is provocation discography. Unfortunately, this procedure is controversial, making the existence of internal disc disruption suspect. Recent studies indicate the existence of a biochemical/ biomechanical model of discogenic pain, which explains the disabling low back pain in some subjects with no objective evidence of nerve-root compromise. However, a reluctance to acknowledge internal disc disruption as a valid clinical entity delays diagnosis and treatment. Failure to identify and treat this entity early and aggressively results in longterm disability, thereby perpetuating the enigma of chronic low back pain.

Entities:  

Year:  2000        PMID: 16906194

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  5 in total

1.  Conservative management of a 31 year old male with left sided low back and leg pain: a case report.

Authors:  Emily R Howell
Journal:  J Can Chiropr Assoc       Date:  2012-09

2.  Clinical and radiological findings of discogenic low back pain confirmed by automated pressure-controlled discography.

Authors:  Hyung-Gon Kim; Dong-Ah Shin; Hyoung-Ihl Kim; Eun-Ae Yoo; Dong-Gyu Shin; Jung-Ok Lee
Journal:  J Korean Neurosurg Soc       Date:  2009-10-31

3.  Clinical outcome following DIAM implantation for symptomatic lumbar internal disk disruption: a 3-year retrospective analysis.

Authors:  Kang Lu; Po-Chou Liliang; Hao-Kuang Wang; Jui-Sheng Chen; Te-Yuan Chen; Ruyi Huang; Han-Jung Chen
Journal:  J Pain Res       Date:  2016-10-31       Impact factor: 3.133

4.  Macrophages Down-Regulate Gene Expression of Intervertebral Disc Degenerative Markers Under a Pro-inflammatory Microenvironment.

Authors:  Ana J Silva; Joana R Ferreira; Carla Cunha; João V Corte-Real; Mafalda Bessa-Gonçalves; Mario A Barbosa; Susana G Santos; Raquel M Gonçalves
Journal:  Front Immunol       Date:  2019-07-03       Impact factor: 7.561

5.  Comparison of Mid- to Long-term Follow-up of Patient-reported Outcomes Measures After Single-level Lumbar Total Disc Arthroplasty, Multi-level Lumbar Total Disc Arthroplasty, and the Lumbar Hybrid Procedure for the Treatment of Degenerative Disc Disease.

Authors:  Matthew Scott-Young; So Mang Simon Lee; David Nielsen; Evelyne Rathbone; Matthew Rackham; Wayne Hing
Journal:  Spine (Phila Pa 1976)       Date:  2022-03-01       Impact factor: 3.468

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.