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28 in total

1. Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.

Authors: Kirsten Famulla; Peter Sass; Imran Malik; Tatos Akopian; Olga Kandror; Marina Alber; Berthold Hinzen; Helga Ruebsamen-Schaeff; Rainer Kalscheuer; Alfred L Goldberg; Heike Brötz-Oesterhelt
Journal: Mol Microbiol Date: 2016-04-01 Impact factor: 3.501

2. Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.

Authors: Karl R Schmitz; Daniel W Carney; Jason K Sello; Robert T Sauer
Journal: Proc Natl Acad Sci U S A Date: 2014-09-29 Impact factor: 11.205

Review 3. Bacterial proteases, untapped antimicrobial drug targets.

Authors: Elizabeth Culp; Gerard D Wright
Journal: J Antibiot (Tokyo) Date: 2016-11-30 Impact factor: 2.649

4. Consequences of Depsipeptide Substitution on the ClpP Activation Activity of Antibacterial Acyldepsipeptides.

Authors: Yangxiong Li; Nathan P Lavey; Jesse A Coker; Jessica E Knobbe; Dat C Truong; Hongtao Yu; Yu-Shan Lin; Susan L Nimmo; Adam S Duerfeldt
Journal: ACS Med Chem Lett Date: 2017-10-19 Impact factor: 4.345

5. Examination of a Structural Model of Peptidomimicry by Cyclic Acyldepsipeptide Antibiotics in Their Interaction with the ClpP Peptidase.

Authors: Daniel W Carney; Karl R Schmitz; Anthony C Scruse; Robert T Sauer; Jason K Sello
Journal: Chembiochem Date: 2015-07-27 Impact factor: 3.164

Medicinal chemistry optimization of acyldepsipeptides of the enopeptin class antibiotics.

1. Acyldepsipeptide antibiotics kill mycobacteria by preventing the physiological functions of the ClpP1P2 protease.

2. Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.

Review 3. Bacterial proteases, untapped antimicrobial drug targets.

4. Consequences of Depsipeptide Substitution on the ClpP Activation Activity of Antibacterial Acyldepsipeptides.

5. Examination of a Structural Model of Peptidomimicry by Cyclic Acyldepsipeptide Antibiotics in Their Interaction with the ClpP Peptidase.

6. Antibiotic acyldepsipeptides activate ClpP peptidase to degrade the cell division protein FtsZ.

Review 7. Advances in MRSA drug discovery: where are we and where do we need to be?

8. Sclerotiamide: The First Non-Peptide-Based Natural Product Activator of Bacterial Caseinolytic Protease P.

9. Specificity Distorted: Chemical Induction of Biological Paracatalysis.

10. Synthetic-Bioinformatic Natural Product Antibiotics with Diverse Modes of Action.