Literature DB >> 16902139

Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis.

Niko Föger1, Linda Rangell, Dimitry M Danilenko, Andrew C Chan.   

Abstract

The evolutionarily conserved actin-related protein (Arp2/3) complex is a key component of actin filament networks that is dynamically regulated by nucleation-promoting and inhibitory factors. Although much is known about actin assembly, the physiologic functions of inhibitory proteins are unclear. We generated coronin 1-/- mice and found that coronin 1 exerted an inhibitory effect on cellular steady-state F-actin formation via an Arp2/3-dependent mechanism. Whereas coronin 1 was required for chemokine-mediated migration, it was dispensable for T cell antigen receptor functions in T cells. Moreover, actin dynamics, through a mitochondrial pathway, was linked to lymphocyte homeostasis.

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Year:  2006        PMID： 16902139     DOI： 10.1126/science.1130563

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  97 in total

Review 1.  Unraveling the enigma: progress towards understanding the coronin family of actin regulators.

Authors:  Keefe T Chan; Sarah J Creed; James E Bear
Journal:  Trends Cell Biol       Date:  2011-06-01       Impact factor: 20.808

2.  GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1A.

Authors:  Daiju Ichikawa; Miho Mizuno; Takashi Yamamura; Sachiko Miyake
Journal:  J Biol Chem       Date:  2011-10-20       Impact factor: 5.157

3.  Functional surfaces on the actin-binding protein coronin revealed by systematic mutagenesis.

Authors:  Meghal Gandhi; Mohini Jangi; Bruce L Goode
Journal:  J Biol Chem       Date:  2010-09-02       Impact factor: 5.157

Review 4.  Breaching multiple barriers: leukocyte motility through venular walls and the interstitium.

Authors:  Sussan Nourshargh; Peter L Hordijk; Michael Sixt
Journal:  Nat Rev Mol Cell Biol       Date:  2010-05       Impact factor: 94.444

5.  Mast cell function is not altered by Coronin-1A deficiency.

Authors:  Sanja Arandjelovic; Dilki Wickramarachchi; Saskia Hemmers; Sunamita S Leming; Dwight H Kono; Kerri A Mowen
Journal:  J Leukoc Biol       Date:  2010-07-19       Impact factor: 4.962

6.  Recurrent viral infections associated with a homozygous CORO1A mutation that disrupts oligomerization and cytoskeletal association.

Authors:  Christina S Yee; Michel J Massaad; Wayne Bainter; Toshiro K Ohsumi; Niko Föger; Andrew C Chan; Nurten A Akarsu; Caner Aytekin; Deniz Çagdas Ayvaz; Ilhan Tezcan; Özden Sanal; Raif S Geha; Janet Chou
Journal:  J Allergy Clin Immunol       Date:  2015-10-21       Impact factor: 10.793

Review 7.  Coronin-1A: immune deficiency in humans and mice.

Authors:  Divya Punwani; Barry Pelz; Jason Yu; Nicoleta C Arva; Kristian Schafernak; Karly Kondratowicz; Melanie Makhija; Jennifer M Puck
Journal:  J Clin Immunol       Date:  2015-02-10       Impact factor: 8.317

8.  Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes.

Authors:  Koko Katagiri; Tomoya Katakai; Yukihiko Ebisuno; Yoshihiro Ueda; Takaharu Okada; Tatsuo Kinashi
Journal:  EMBO J       Date:  2009-04-02       Impact factor: 11.598

Review 9.  Immune pathology associated with altered actin cytoskeleton regulation.

Authors:  Dilki C Wickramarachchi; Argyrios N Theofilopoulos; Dwight H Kono
Journal:  Autoimmunity       Date:  2010-02       Impact factor: 2.815

10.  Proof of Principle for a T Lymphocyte Intrinsic Function of Coronin 1A.

Authors:  Kerstin Siegmund; Victoria Klepsch; Natascha Hermann-Kleiter; Gottfried Baier
Journal:  J Biol Chem       Date:  2016-08-26       Impact factor: 5.157
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