Literature DB >> 16899356

The antitumor and antioxidative activities of polysaccharides isolated from Isaria farinosa B05.

Yan-Hua Jiang1, Xiao-Lu Jiang, Peng Wang, Hai-Jin Mou, Xiao-Ke Hu, Shu-Qing Liu.   

Abstract

The water-soluble intra-polysaccharides WIPS1 and water-soluble extra-polysaccharides WEPS1 were isolated from Isaria farinosa B05 through ethanol precipitation and gel permeation chromatography (GPC). Their characteristics were determined by chemical analysis, gas chromatography, GPC and IR spectroscopy. The results show that WIPS1 contained 90.3% carbohydrate, 8.00% uronic acid, 7.15% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 8.0:4.8:1.0. WEPS1 contained 93.4% carbohydrate, 8.06% uronic acid, 4.40% protein and three kinds of monosaccharides including mannose, galactose and glucose with a molar ratio of 21.6:4.7:1.0. WIPS1 and WEPS1 had a molecular weight of 42 and 208kDa, respectively. The in vivo tests in mice indicate that WIPS1 and WEPS1 had significant antitumor and antioxidative activities to some extent.

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Year:  2006        PMID: 16899356     DOI: 10.1016/j.micres.2006.07.002

Source DB:  PubMed          Journal:  Microbiol Res        ISSN: 0944-5013            Impact factor:   5.415


  5 in total

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Journal:  Microbiol Insights       Date:  2013-01-29

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3.  The assessment of anti-tumoral activity of polysaccharide extracted from terrestrial filamentous fungus.

Authors:  Behzad Salehi; Mansour Bayat; Mehrouz Dezfulian; Azar Sabokbar; Bahman Tabaraie
Journal:  Saudi J Biol Sci       Date:  2016-06-17       Impact factor: 4.219

4.  Culture conditions and nutrition requirements for the mycelial growth of Isaria farinosa (Hypocreales: Cordycipitaceae) and the altitude effect on its growth and metabolome.

Authors:  Fei Liu; Meichun Xiang; Yanlei Guo; Xiaoli Wu; Guangxin Lu; Yong Yang; Xingzhong Liu; Shijiang Chen; Guozhen Zhang; Wangpeng Shi
Journal:  Sci Rep       Date:  2018-10-23       Impact factor: 4.379

5.  Optimization of fermentation process of Cordyceps militaris and antitumor activities of polysaccharides in vitro.

Authors:  Shuang Yang; Lu Jin; Xiaodong Ren; Jiahui Lu; Qingfan Meng
Journal:  J Food Drug Anal       Date:  2014-05-22       Impact factor: 6.157

  5 in total

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