| Literature DB >> 1689358 |
R E Banks1, S W Evans, F Van Leuven, D Alexander, M J McMahon, J T Whicher.
Abstract
A sandwich enzyme immunoassay has been developed for measuring the 'fast' or complexed form of alpha 2 macroglobulin using a complex-specific monoclonal antibody. The working range of this assay is 1.5-15 micrograms/l and is suitable for use with various biological fluids. Using this assay the normal plasma levels were found to range from 4.2 mg/l to 14.4 mg/l (0.17%-0.70% of total alpha 2 macroglobulin) with a mean value of 7.6 mg/l +/- 2.6 (0.37% +/- 0.12% of total alpha 2 macroglobulin). Elevated levels were seen in plasma samples taken on the day of admission from patients with acute pancreatitis and in some synovial fluid samples from patients with various arthritides.Entities:
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Year: 1990 PMID： 1689358 DOI： 10.1016/0022-1759(90)90006-h
Source DB: PubMed Journal: J Immunol Methods ISSN： 0022-1759 Impact factor: 2.303