Literature DB >> 16885551

Validation of a rule for termination of resuscitation in out-of-hospital cardiac arrest.

Laurie J Morrison1, Laura M Visentin, Alex Kiss, Rob Theriault, Don Eby, Marian Vermeulen, Jonathan Sherbino, P Richard Verbeek.   

Abstract

BACKGROUND: We prospectively evaluated a clinical prediction rule to be used by emergency medical technicians (EMTs) trained in the use of an automated external defibrillator for the termination of basic life support resuscitative efforts during out-of-hospital cardiac arrest. The rule recommends termination when there is no return of spontaneous circulation, no shocks are administered, and the arrest is not witnessed by emergency medical-services personnel. Otherwise, the rule recommends transportation to the hospital, in accordance with routine practice.
METHODS: The study included 24 emergency medical systems in Ontario, Canada. All patients 18 years of age or older who had an arrest of presumed cardiac cause and who were treated by EMTs trained in the use of an automated external defibrillator were included. The patients were treated according to standard guidelines. Characteristics of diagnostic tests for the prediction rule were calculated. These characteristics include sensitivity, specificity, and positive and negative predictive values.
RESULTS: Follow-up data were obtained for all 1240 patients. Of 776 patients with cardiac arrest for whom the rule recommended termination, 4 survived (0.5 percent). The rule had a specificity of 90.2 percent for recommending transport of survivors to the emergency department and had a positive predictive value for death of 99.5 percent when termination was recommended. Implementation of this rule would result in a decrease in the rate of transportation from 100 percent of patients to 37.4 percent. The addition of other criteria (a response interval greater than eight minutes or a cardiac arrest not witnessed by a bystander) would further improve both the specificity and positive predictive value of the rule but would result in the transportation of a larger proportion of patients.
CONCLUSIONS: The use of a clinical prediction rule for the termination of resuscitation may help clinicians decide whether to terminate basic life support resuscitative efforts in patients having an out-of-hospital cardiac arrest. Copyright 2006 Massachusetts Medical Society.

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Year:  2006        PMID: 16885551     DOI: 10.1056/NEJMoa052620

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


  50 in total

Review 1.  [Prognostic assessment as the basis for limiting therapy in unconscious patients after cardiopulmonary resuscitation].

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2.  Postresuscitation accelerated idioventricular rhythm: a potential prognostic factor for out-of-hospital cardiac arrest survivors.

Authors:  Min-Shan Tsai; Chien-Hua Huang; Hung-Ren Chen; Cheng-Chun Hsieh; Wei-Tien Chang; Chiung-Yuan Hsu; Matthew Huei-Ming Ma; Shyr-Chyr Chen; Wen-Jone Chen
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3.  Is it possible to terminate resuscitation in accordance with the termination of resuscitation rule?

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Journal:  J Thorac Dis       Date:  2016-10       Impact factor: 2.895

4.  A comparison of the universal TOR Guideline to the absence of prehospital ROSC and duration of resuscitation in predicting futility from out-of-hospital cardiac arrest.

Authors:  Ian R Drennan; Erin Case; P Richard Verbeek; Joshua C Reynolds; Zachary D Goldberger; Jamie Jasti; Mark Charleston; Heather Herren; Ahamed H Idris; Paul R Leslie; Michael A Austin; Yan Xiong; Robert H Schmicker; Laurie J Morrison
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5.  What should we consider when applying termination of resuscitation rules?

Authors:  Jae Chol Yoon; Won Young Kim
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6.  Should we resuscitate or not-that is the question!

Authors:  Michael Bernhard; Torben Kim Becker; Björn Hossfeld
Journal:  J Thorac Dis       Date:  2016-06       Impact factor: 2.895

7.  Variability in the initiation of resuscitation attempts by emergency medical services personnel during out-of-hospital cardiac arrest.

Authors:  Steven C Brooks; Robert H Schmicker; Sheldon Cheskes; Jim Christenson; Alan Craig; Mohamud Daya; Peter J Kudenchuk; Graham Nichol; Dana Zive; Laurie J Morrison
Journal:  Resuscitation       Date:  2017-06-15       Impact factor: 5.262

8.  Association of Intra-arrest Transport vs Continued On-Scene Resuscitation With Survival to Hospital Discharge Among Patients With Out-of-Hospital Cardiac Arrest.

Authors:  Brian Grunau; Noah Kime; Brian Leroux; Thomas Rea; Gerald Van Belle; James J Menegazzi; Peter J Kudenchuk; Christian Vaillancourt; Laurie J Morrison; Jonathan Elmer; Dana M Zive; Nancy M Le; Michael Austin; Neal J Richmond; Heather Herren; Jim Christenson
Journal:  JAMA       Date:  2020-09-15       Impact factor: 56.272

9.  Characteristics and prognosis of sudden cardiac death in Greater Paris: population-based approach from the Paris Sudden Death Expertise Center (Paris-SDEC).

Authors:  Wulfran Bougouin; Lionel Lamhaut; Eloi Marijon; Daniel Jost; Florence Dumas; Nicolas Deye; Frankie Beganton; Jean-Philippe Empana; Emilie Chazelle; Alain Cariou; Xavier Jouven
Journal:  Intensive Care Med       Date:  2014-03-22       Impact factor: 17.440

10.  Usefulness of the bispectral index during cardiopulmonary resuscitation -A case report-.

Authors:  Jin Yong Jung; Yeonbaek Kim; Jung-Eun Kim
Journal:  Korean J Anesthesiol       Date:  2013-01-21
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