Literature DB >> 16880542

Structure of apo-glyceraldehyde-3-phosphate dehydrogenase from Synechococcus PCC7942.

Tomoya Kitatani1, Yoshihiro Nakamura, Kei Wada, Takayoshi Kinoshita, Masahiro Tamoi, Shigeru Shigeoka, Toshiji Tada.   

Abstract

The crystal structure of NADP-dependent apo-glyceraldehyde-3-phosphate dehydrogenase (apo-GAPDH) from Synechococcus PCC 7942 is reported. The crystal structure was solved by molecular replacement and refined to an R of 21.7% and R(free) of 27.5% at 2.9 angstroms resolution. The structural features of apo-GAPDH are as follows. The S-loop has an extremely flexible conformation and the sulfate ion is only taken into the classical P(i) site. A structural comparison with holo-GAPDHs indicated that the S-loop fixation is essential in the discrimination of NADP and NAD molecules.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16880542      PMCID： PMC2242934          DOI： 10.1107/S1744309106027916

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


  24 in total

1.  Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase.

Authors:  D Moras; K W Olsen; M N Sabesan; M Buehner; G C Ford; M G Rossmann
Journal:  J Biol Chem       Date:  1975-12-10       Impact factor: 5.157

2.  The small protein CP12: a protein linker for supramolecular complex assembly.

Authors:  Emmanuelle Graciet; Pierre Gans; Norbert Wedel; Sandrine Lebreton; Jean-Michel Camadro; Brigitte Gontero
Journal:  Biochemistry       Date:  2003-07-15       Impact factor: 3.162

3.  Crystallography & NMR system: A new software suite for macromolecular structure determination.

Authors:  A T Brünger; P D Adams; G M Clore; W L DeLano; P Gros; R W Grosse-Kunstleve; J S Jiang; J Kuszewski; M Nilges; N S Pannu; R J Read; L M Rice; T Simonson; G L Warren
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1998-09-01

4.  Glyceraldehyde-3-phosphate dehydrogenase (NADP) from Sinapis alba L. NAD(P)-induced conformation changes of the enzyme.

Authors:  R Cerff
Journal:  Eur J Biochem       Date:  1978-01-02

5.  Crystal structure of the non-regulatory A(4 )isoform of spinach chloroplast glyceraldehyde-3-phosphate dehydrogenase complexed with NADP.

Authors:  S Fermani; A Ripamonti; P Sabatino; G Zanotti; S Scagliarini; F Sparla; P Trost; P Pupillo
Journal:  J Mol Biol       Date:  2001-11-30       Impact factor: 5.469

6.  CP12 provides a new mode of light regulation of Calvin cycle activity in higher plants.

Authors:  N Wedel; J Soll; B K Paap
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-16       Impact factor: 11.205

7.  Crystal structure of Leishmania mexicana glycosomal glyceraldehyde-3-phosphate dehydrogenase in a new crystal form confirms the putative physiological active site structure.

Authors:  H Kim; W G Hol
Journal:  J Mol Biol       Date:  1998-04-24       Impact factor: 5.469

8.  The Calvin cycle in cyanobacteria is regulated by CP12 via the NAD(H)/NADP(H) ratio under light/dark conditions.

Authors:  Masahiro Tamoi; Takashi Miyazaki; Tamo Fukamizo; Shigeru Shigeoka
Journal:  Plant J       Date:  2005-05       Impact factor: 6.417

9.  Structural analysis of glyceraldehyde 3-phosphate dehydrogenase from Escherichia coli: direct evidence of substrate binding and cofactor-induced conformational changes.

Authors:  M Yun; C G Park; J Y Kim; H W Park
Journal:  Biochemistry       Date:  2000-09-05       Impact factor: 3.162

10.  Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.

Authors:  Takayoshi Kinoshita; Riyo Maruki; Masaichi Warizaya; Hidenori Nakajima; Shintaro Nishimura
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-03-24
View more
  3 in total

1.  Structure of photosynthetic glyceraldehyde-3-phosphate dehydrogenase (isoform A4) from Arabidopsis thaliana in complex with NAD.

Authors:  Simona Fermani; Francesca Sparla; Lucia Marri; Anton Thumiger; Paolo Pupillo; Giuseppe Falini; Paolo Trost
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-05-25

2.  Structural snapshots of nitrosoglutathione binding and reactivity underlying S-nitrosylation of photosynthetic GAPDH.

Authors:  Edoardo Jun Mattioli; Jacopo Rossi; Maria Meloni; Marcello De Mia; Christophe H Marchand; Andrea Tagliani; Silvia Fanti; Giuseppe Falini; Paolo Trost; Stéphane D Lemaire; Simona Fermani; Matteo Calvaresi; Mirko Zaffagnini
Journal:  Redox Biol       Date:  2022-06-30       Impact factor: 10.787

3.  A cryoprotectant induces conformational change in glyceraldehyde-3-phosphate dehydrogenase.

Authors:  Yong Ju Kim
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2018-04-16       Impact factor: 1.056
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.