Literature DB >> 16873494

An experimental metagenome data management and analysis system.

Victor M Markowitz1, Natalia Ivanova, Krishna Palaniappan, Ernest Szeto, Frank Korzeniewski, Athanasios Lykidis, Iain Anderson, Konstantinos Mavromatis, Konstantinos Mavrommatis, Victor Kunin, Hector Garcia Martin, Inna Dubchak, Phil Hugenholtz, Nikos C Kyrpides.   

Abstract

The application of shotgun sequencing to environmental samples has revealed a new universe of microbial community genomes (metagenomes) involving previously uncultured organisms. Metagenome analysis, which is expected to provide a comprehensive picture of the gene functions and metabolic capacity for microbial communities, needs to be conducted in the context of a comprehensive data management and analysis system. We present in this paper IMG/M, an experimental metagenome data management and analysis system that is based on the Integrated Microbial Genomes (IMG) system. IMG/M provides tools and viewers for analyzing both metagenomes and isolate genomes individually or in a comparative context. IMG/M is available at http://img.jgi.doe.gov/m.

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Year:  2006        PMID: 16873494     DOI: 10.1093/bioinformatics/btl217

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  27 in total

1.  Dissecting biological "dark matter" with single-cell genetic analysis of rare and uncultivated TM7 microbes from the human mouth.

Authors:  Yann Marcy; Cleber Ouverney; Elisabeth M Bik; Tina Lösekann; Natalia Ivanova; Hector Garcia Martin; Ernest Szeto; Darren Platt; Philip Hugenholtz; David A Relman; Stephen R Quake
Journal:  Proc Natl Acad Sci U S A       Date:  2007-07-09       Impact factor: 11.205

2.  Structure of the ribosomal interacting GTPase YjeQ from the enterobacterial species Salmonella typhimurium.

Authors:  C E Nichols; C Johnson; H K Lamb; M Lockyer; I G Charles; A R Hawkins; D K Stammers
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2007-10-24

Review 3.  A bioinformatician's guide to metagenomics.

Authors:  Victor Kunin; Alex Copeland; Alla Lapidus; Konstantinos Mavromatis; Philip Hugenholtz
Journal:  Microbiol Mol Biol Rev       Date:  2008-12       Impact factor: 11.056

4.  Laboratory procedures to generate viral metagenomes.

Authors:  Rebecca V Thurber; Matthew Haynes; Mya Breitbart; Linda Wegley; Forest Rohwer
Journal:  Nat Protoc       Date:  2009       Impact factor: 13.491

5.  Functional divergence outlines the evolution of novel protein function in NifH/BchL protein family.

Authors:  Subarna Thakur; Asim K Bothra; Arnab Sen
Journal:  J Biosci       Date:  2013-11       Impact factor: 1.826

6.  Characterization of pseudogenes in members of the order Frankineae.

Authors:  Saubashya Sur; Sangita Saha; Louis S Tisa; Asim K Bothra; Arnab Sen
Journal:  J Biosci       Date:  2013-11       Impact factor: 1.826

7.  Comparative investigation of the various determinants that influence the codon and amino acid usage patterns in the genus Bifidobacterium.

Authors:  Ayan Roy; Subhasish Mukhopadhyay; Indrani Sarkar; Arnab Sen
Journal:  World J Microbiol Biotechnol       Date:  2015-04-05       Impact factor: 3.312

8.  A biological treasure metagenome: pave a way for big science.

Authors:  So-Youn Park; Geun-Joong Kim
Journal:  Indian J Microbiol       Date:  2008-07-27       Impact factor: 2.461

Review 9.  Marine metagenomics: new tools for the study and exploitation of marine microbial metabolism.

Authors:  Jonathan Kennedy; Burkhardt Flemer; Stephen A Jackson; David P H Lejon; John P Morrissey; Fergal O'Gara; Alan D W Dobson
Journal:  Mar Drugs       Date:  2010-03-15       Impact factor: 5.118

10.  Evaluation of the bacterial diversity among and within individual venous leg ulcers using bacterial tag-encoded FLX and titanium amplicon pyrosequencing and metagenomic approaches.

Authors:  Randall D Wolcott; Viktoria Gontcharova; Yan Sun; Scot E Dowd
Journal:  BMC Microbiol       Date:  2009-10-27       Impact factor: 3.605

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