| Literature DB >> 1687346 |
N E Allen1, W E Alborn, J N Hobbs.
Abstract
Daptomycin inhibits the formation of UDP-N-acetylmuramyl-pentapeptide in Bacillus megaterium by inhibiting active transport of amino acids incorporated into the pentapeptide. The ability of daptomycin to inhibit active transport and peptidoglycan formation may be due to its ability to disrupt the transmembrane electrochemical gradient.Entities:
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Year: 1991 PMID: 1687346 PMCID: PMC245446 DOI: 10.1128/AAC.35.12.2639
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191