OBJECTIVE: To assess added value of a booster dose of a tailored mammography intervention. METHODS:Participants, non-adherent at baseline, were randomly assigned to usual care or one of three tailored interventions. Intervention group members (n=657) were further randomly assigned to receive/not receive a booster intervention dose. Electronic record mammography data were collected following initial intervention and at 6 and 15 months post-booster. RESULTS: Booster had no effect among women not screened after first intervention dose (n=337). Among women screened after initial dose (n=320), booster predicted re-screening at 6 but not 15 months. A boosterxrace interaction showed a booster effect at 6 months for African Americans (OR=4.66, p=.0005) but not Caucasians (OR=0.74, p=.44). CONCLUSIONS: Findings suggest if a first-dose intervention does not facilitate screening, neither will a booster dose. However, among women for whom a first dose is effective, boosters can facilitate timely repeat adherence, especially among African Americans. At 6 months booster recipients were less likely to be off-schedule but, by 15 months, the groups were similar. PRACTICE IMPLICATIONS: Boosters may effect when, but not whether, women continue screening.
RCT Entities:
OBJECTIVE: To assess added value of a booster dose of a tailored mammography intervention. METHODS:Participants, non-adherent at baseline, were randomly assigned to usual care or one of three tailored interventions. Intervention group members (n=657) were further randomly assigned to receive/not receive a booster intervention dose. Electronic record mammography data were collected following initial intervention and at 6 and 15 months post-booster. RESULTS: Booster had no effect among women not screened after first intervention dose (n=337). Among women screened after initial dose (n=320), booster predicted re-screening at 6 but not 15 months. A boosterxrace interaction showed a booster effect at 6 months for African Americans (OR=4.66, p=.0005) but not Caucasians (OR=0.74, p=.44). CONCLUSIONS: Findings suggest if a first-dose intervention does not facilitate screening, neither will a booster dose. However, among women for whom a first dose is effective, boosters can facilitate timely repeat adherence, especially among African Americans. At 6 months booster recipients were less likely to be off-schedule but, by 15 months, the groups were similar. PRACTICE IMPLICATIONS: Boosters may effect when, but not whether, women continue screening.
Authors: Caitlin C Murphy; Chul Ahn; Sandi L Pruitt; Amy E Hughes; Ethan A Halm; Samir Gupta; Noel O Santini; Katharine McCallister; Joanne M Sanders; Amit G Singal; Celette Sugg Skinner Journal: Prev Med Date: 2018-12-01 Impact factor: 4.018
Authors: Sally W Vernon; Deborah J Del Junco; Sharon P Coan; Caitlin C Murphy; Scott T Walters; Robert H Friedman; Lori A Bastian; Deborah A Fisher; David R Lairson; Ronald E Myers Journal: Contemp Clin Trials Date: 2021-04-03 Impact factor: 2.261